ArticleFrontiers in veterinary science2021
Pulmonary Vascular Resistance Estimated by Echocardiography in Dogs With Myxomatous Mitral Valve Disease and Pulmonary Hypertension Probability.
Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 12 citations in OpenAlex.
- Comparison and Agreement of Echocardiographic Volumetric Methods for Quantifying Mitral Regurgitation in Dogs with Myxomatous Mitral Valve Disease.Animals : an open access journal from MDPI · 2026Article
- One Health Insights into Pulmonary Hypertension: Bridging Human and Canine Medicine.Veterinary sciences · 2026Review
- Echocardiographic evaluation of pulmonary vascular resistance in 459 dogs with Doppler-derived pulmonary hypertension.Journal of veterinary internal medicine · 2026Article
- Short-term changes in clinical status, cardiovascular function and heart rate variability after staphylectomy and alarplasty in French Bulldogs with brachycephalic obstructive airway syndrome.BMC veterinary research · 2026Article
- Prevalence of iron deficiency and its association with cardiac function in dogs with various stages of myxomatous mitral valvular disease.Frontiers in veterinary science · 2026Article
- Quantitative mitral regurgitation and conventional echocardiographic variables in canine myxomatous mitral valve disease.Frontiers in veterinary science · 2026Article
- Urinary NGAL as an Early Marker of Renal Dysfunction in Dogs with Heartworm Disease and Pulmonary Hypertension.Animals : an open access journal from MDPI · 2025Article
- Animal models of pulmonary hypertension due to left heart disease.Animal models and experimental medicine · 2022Review
- Beraprost Sodium for Pulmonary Hypertension in Dogs: Effect on Hemodynamics and Cardiac Function.Animals : an open access journal from MDPI · 2022Article
- Utility of Real-Time Three-Dimensional Echocardiography for the Assessment of Right Ventricular Morphology and Function in Large Animal Models.Journal of clinical medicine · 2022Article
- Investigation of Beraprost Sodium on Cardiac Function and Hemodynamics in Canine Models of Chronic Pulmonary Hypertension.Frontiers in veterinary science · 2022Article
- The echocardiographic pulmonary to left atrial ratio: A noninvasive variable for the hemodynamic classification of pulmonary hypertension in dogs.Journal of veterinary internal medicineArticle
- Prognostic value of pulmonary vascular resistance estimated by echocardiography in dogs with myxomatous mitral valve disease and pulmonary hypertension.Journal of veterinary internal medicineArticle
- Pulmonary thrombotic pulmonary hypertension managed using antithrombotic and pulmonary vasodilator treatment.Journal of veterinary internal medicineArticle
- Echocardiographic characteristics of dogs with pulmonary hypertension secondary to respiratory diseases.Journal of veterinary internal medicineArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Post-capillary pulmonary hypertension (PH) is a life-threatening complication in dogs with myxomatous mitral valve disease (MMVD). An increase in pulmonary vascular resistance (PVR) is associated with post-capillary PH progression. In humans, PVR estimated by echocardiography (PVRecho) enables the non-invasive assessment of PVR in patients with PH. This study aimed to evaluate the clinical utility of PVRecho in dogs with MMVD, PH probability, and right-sided congestive heart failure (R-CHF). Dogs with MMVD and detectable tricuspid valve regurgitation were included in the study. Dogs were classified into three PH probability groups (low/intermediate/high) and according to the presence or absence of R-CHF. All dogs underwent echocardiographic measurements for right ventricular (RV) morphology and function. PVRecho was calculated by two methods using tricuspid valve regurgitation velocity and velocity-time integral of the pulmonary artery flow (PVRecho and PVRecho2). RV size indicators were significantly higher with a higher probability of PH. RV strain and velocity-time integral of the pulmonary artery flow in the high probability group were significantly lower than those in the other groups. Tricuspid valve regurgitation velocity, PVRecho, and PVRecho2 were significantly higher with an increase in PH probability. Logistic regression analysis revealed a significant association between the presence of R-CHF and increased PVRecho2 and end-diastolic RV internal dimension normalized by body weight. PVRecho and PVRecho2 showed significant differences among the PH probability groups. These non-invasive variables may be useful for the diagnosis and stratification of PH and the determination of the presence of R-CHF in dogs with MMVD.
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