Evidence map›Paper›PMID 34765606›Full record

ArticleFrontiers in cell and developmental biology2021

A Screen of Autophagy Compounds Implicates the Proteasome in Mammalian Aminoglycoside-Induced Hair Cell Damage.

Clara Draf, Taylor Wyrick, Eduardo Chavez, Kwang Pak, Arwa Kurabi, Anke Leichtle, Stefan Dazert, Allen F Ryan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Clara DrafDepartment of Surgery/Otolaryngology, University of California, San Diego, San Diego, CA, United States.
Taylor WyrickDepartment of Biology, University of California, San Diego, San Diego, CA, United States.
Eduardo ChavezDepartment of Surgery/Otolaryngology, University of California, San Diego, San Diego, CA, United States.
Kwang PakDepartment of Surgery/Otolaryngology, University of California, San Diego, San Diego, CA, United States.
Arwa KurabiDepartment of Surgery/Otolaryngology, University of California, San Diego, San Diego, CA, United States.
Anke LeichtleDepartment of Otolaryngology, University Medical Center Schleswig-Holstein, Lübeck, Germany.
Stefan DazertDepartment of Otolaryngology, St. Elisabeth-Hospital, Ruhr University Bochum, Bochum, Germany.
Allen F RyanDepartment of Surgery/Otolaryngology, University of California, San Diego, San Diego, CA, United States.
University of California, San Diego · USRuhr University Bochum · DEUniversity Hospital Schleswig-Holstein · DEVA San Diego Healthcare System · US

Funding

Basic Mechanisms on Hearing Loss of Cochlear OriginI01BX001205 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI RYAN, ALLEN F. · 2013 to 2024
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BLRD VA I01 BX001205
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

aminoglycoside–ototoxicityautophagyhair cellinner earin vitro screen

Identifiers

PMID34765606
PMCPMC8576371
OpenAlexW3211023422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.