ArticleTranslational pediatrics2021
Effect of adenoid hypertrophy on the upper airway and craniomaxillofacial region.
Article in Translational pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 32 citations in OpenAlex.
- Effect of bonded lingual spurs with low trans palatal arch on developing anterior open bite (a randomized controlled trial).BMC oral health · 2026Trial
- Increased IL-5, IL-33, and ST2 expression in pediatric adenoid hypertrophy associated with allergic rhinitis: Immunohistochemical and systemic evidence.Irish journal of medical science · 2026Article
- Biomechanical and Aerodynamic Modulation for Sinonasal Homeostasis in Craniofacial Orthopedics: A Comprehensive Review of RAMPA Therapy.Biomimetics (Basel, Switzerland) · 2026Review
- Age-stratified study on symptoms of upper airway obstruction and craniofacial development in children.BMC oral health · 2026Article
- Multidimensional analysis of the impact of adenoid hypertrophy on pediatric dentofacial and airway structures and construction of a diagnostic model.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Upper airway dimensions in adolescents with different craniofacial growth patterns: a retrospective cross-sectional comparison of independent samples from 2005 and 2020.BMC oral health · 2026Article
- Enhancing airway obstruction diagnosis with multimodal 3D shape analysis.International journal of computer assisted radiology and surgery · 2026Article
- Predictive Value of Neck-to-Height Ratio in Children with Moderate/Severe Obstructive Sleep Apnea: A Retrospective Cross-Sectional Study.Nature and science of sleep · 2026Article
- Exploring the nonlinear association between serum uric acid and the TG/HDL-C Ratio: insights from school-aged children with adenoid or tonsillar hypertrophy.Frontiers in public health · 2026Article
- Comparison of craniofacial skeletal morphology in pediatric obstructive sleep apnea-hypopnea syndrome patients with class II and class III malocclusions: a retrospective cross-sectional study.Frontiers in pediatrics · 2026Article
- Evaluation of Oral Health and Oral Health-Related Quality of Life in Children with Adenoid Hypertrophy.Children (Basel, Switzerland) · 2025Article
- Feasibility study of fully automatic measurement of adenoid size on lateral neck and head radiographs using deep learning.Pediatric radiology · 2025Article
- Bidirectional Relationship Between Dental Diseases and Sleep Disturbances in Pediatric Patients.Clinical and experimental dental research · 2025Review
- Article
- The Role of Type 2 Innate Lymphoid Cells in Adenoid Hypertrophy with Allergic Rhinitis Among Children and Related Potential Therapeutic Targets.Journal of inflammation research · 2025Article
- Age-group-specific associations between adenoid/tonsillar hypertrophy and craniofacial features.BMC oral health · 2024Article
- Preliminary Investigation into the Association between Scoliosis and Hypoxia: A Retrospective Cohort Study on the Impact of Eliminating Hypoxic Factors on Scoliosis Outcomes.Children (Basel, Switzerland) · 2024Article
- Allergen Immunotherapy for a Year Can Effectively Reduce the Risk of Postoperative Recurrence of Adenoid Hypertrophy in Children with Concurrent Allergic Rhinitis (IMPROVEII).Journal of asthma and allergy · 2024Article
- Adenoid facies: a long-term vicious cycle of mouth breathing, adenoid hypertrophy, and atypical craniofacial development.Frontiers in public health · 2024Review
- Influences of Adenoid Hypertrophy on Children's Maxillofacial Development.Healthcare (Basel, Switzerland) · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn recent years, annual incidences of adenoid hypertrophy (AH), a highly common tissue lesion in children, have increased. Currently, research on AH has focused on its obstruction of nasal cavity function, and little has been written on its influence on the upper airway's bone structure. For this reason, our present study seeks to determine the influence of AH on both the morphological development characteristics of the upper airway and the craniofacial features in children, with the goal being to offer more choices for diagnosing and treating the condition in the future.
methodsFrom June 2019 to December 2020 in Department of Orthodontics, Beijing Stomatological Hospital, Capital Medical University, 38 children with AH admitted to the Department of Otolaryngology [research group (RG)] and 35 children [control group (CG)] who underwent orthodontic treatment over the same time span were selected as the research objects. X-ray examination of the lateral position of the head, observation of the maxillofacial structure, and detection of the children's height, growth factors, and sleep status, and analysis of the differences between the two groups.
resultsThe height of RG, insulin-like growth factor-1 (IGF-1) as well as insulin-like growth factor binding protein-3 (IGFBP-3) were all lower than CG (P<0.05), the upper airway became narrower, and the malocclusion was aggravated (P<0.05). Cephalometric measurement showed that the angle between the subspinale and sella at nasion (SNA angle) and the angle between the subspinale and supraemental at nasion (ANB angle) of RG children decreased, and the angle between the supraemental and sella at nasion (SNB angle) increased (P<0.05). In addition, the sleep quality of RG was significantly lower than that of CG (P<0.05).
conclusionsAH can change a child's breathing mode and function by giving rise to upper airway stenosis, and by inducing deformities of their craniomaxillofacial region and oral cavity, thus disrupting their normal growth and development.
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