Evidence map›Paper›PMID 34765303›Full record

ArticleAmerican journal of cancer research2021

Complete response at first transarterial chemoembolization predicts favorable outcome in hepatocellular carcinoma.

Chien-Wei Peng, Wei Teng, Kar-Wai Lui, Chien-Fu Hung, Wen-Juei Jeng, Chien-Hao Huang, Wei-Ting Chen, Chen-Chun Lin, Chun-Yen Lin, Shi-Ming Lin and 1 more

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Chien-Wei PengDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taiwan.
Wei TengDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taiwan.
Kar-Wai LuiDepartment of Medical Imaging & Intervention, Chang Gung Memorial Hospital at Linkou Taoyuan, Taiwan.
Chien-Fu HungDepartment of Radiology, Tucheng Composite Municipal Hospital Taiwan.
Wen-Juei JengDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taiwan.
Chien-Hao HuangDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taiwan.
Wei-Ting ChenDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taiwan.
Chen-Chun LinDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taiwan.
Chun-Yen LinDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taiwan.
Shi-Ming LinDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taiwan.
I-Shyan SheenDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taiwan.
Chang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transarterial chemoembolization (TACE) is the mainstay of treatment for patients with intermediate/advanced stage or unresectable hepatocellular carcinoma (HCC). Despite the palliative nature of TACE treatment, embolizing the tumor feeding vessels and leading to progressive tumor necrosis, complete response (CR) after TACE could still be observed in a certain population. Thus, this study aimed to investigate both the predictors for CR and the long-term prognosis of the patients with CR after TACE. The study recruited new diagnosed HCC patients initially treated with TACE from 2010 to 2013. Post TACE response was assessed by scheduled image studies according to the modified Response Evaluation Criteria in Solid Tumors (mRECIST). Then, pre-TACE factors were compared between patients with and without CR. After the first session of TACE, 22.3% of the 669 TACE treated patients achieved CR. During a median of 26.6 months follow-up, patients with CR had better overall survival than those without (median: 35.8 vs. 24.0 months,

Indexed as

Complete responsepredictorsprognosisTACE

Identifiers

PMID34765303
PMCPMC8569367
OpenAlexW3212156584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.