Evidence map›Paper›PMID 34765262›Full record

ArticleCardiology research and practice2021

NT-proBNP and Major Adverse Cardiovascular Events in Patients with ST-Segment Elevation Myocardial Infarction Who Received Primary Percutaneous Coronary Intervention: A Prospective Cohort Study.

Zuoan Qin, Yaoyao Du, Quan Zhou, Xuelin Lu, Li Luo, Zhixiang Zhang, Ning Guo, Liangqing Ge

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cardiology research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06569511 (Predictive Value of NT-proBNP on Major Adverse Cardiovascular Events in Patients With Acute Coronary Syndrome During a 6-month Follow-up), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06569511 completednot on this mapstarted 2023, after this paper: background citation

Predictive Value of NT-proBNP on Major Adverse Cardiovascular Events in Patients With Acute Coronary Syndrome During a 6-month Follow-up

TypeobservationalSponsorHaseki Training and Research HospitalRan2023 to 2024Enrolled241ConditionsAcute Coronary Syndrome, ST-segment Elevation Myocardial Infarction (STEMI), Non-ST-Segment Elevation Myocardial Infarction (NSTEMI), Major Adverse Cardiac EventsArmsN-terminal pro-B-type natriuretic peptide (NT-proBNP), high sensitive cardiac troponin T (hs-cTnT)
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  13. Risk factors and prediction nomogram model for 1-year readmission for major adverse cardiovascular events in patients with STEMI after PCI.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zuoan QinDepartment of Cardiology, The First People's Hospital of Changde City, Changde 415003, China.ORCID https://orcid.org/0000-0002-0783-3641
Yaoyao DuJishou University, Jishou 416000, China.
Quan ZhouDepartment of Science and Education, The First People's Hospital of Changde City, Changde 415003, China.
Xuelin LuDepartment of Pathology, The First People's Hospital of Changde City, Changde 415003, China.
Li LuoDepartment of Cardiology, The First People's Hospital of Changde City, Changde 415003, China.
Zhixiang ZhangDepartment of Cardiology, The First People's Hospital of Changde City, Changde 415003, China.
Ning GuoDepartment of Cardiology, The First People's Hospital of Changde City, Changde 415003, China.
Liangqing GeDepartment of Cardiology, The First People's Hospital of Changde City, Changde 415003, China.ORCID https://orcid.org/0000-0002-4593-6908
The First People's Hospital of Changde · CNJinan University · CNJishou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prognostic significance of the amino-terminal fragment of the prohormone brain-type natriuretic peptide (NT-proBNP) in patients with ST-segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI) has not been fully elucidated. Major adverse cardiovascular events (MACEs) are clinically viable indicators for the accurate, rapid, and safe evaluation of patients with STEMI. This study was designed to investigate the relationship between NT-proBNP levels and the occurrence of short-term MACEs in patients with STEMI who underwent emergency PCI.

methodsThis prospective cohort study included 405 patients with STEMI aged 20-90 years who underwent emergency PCI at the First People's Hospital of Changde City from April 6, 2017, to May 31, 2019. Stent thrombosis, reinfarction, congestive heart failure, unstable angina, and cardiac death were considered as MACEs in this study. The target-independent and -dependent variables were NT-proBNP at baseline and MACE, respectively.

resultsThere were 28.25% of MACEs. Age, number of implanted stents, Killip class, infarction-related artery, applied intra-aortic balloon pump (IABP), creatine kinase (CK) peak value, CK-MB peak value, TnI peak value, and ST-segment resolution were independently associated with MACE (

conclusionsIn patients with STEMI who underwent PCI, Log2 NT-proBNP was positively correlated with MACE within 1 month when the Log2 NT-proBNP was >11.66 (NT-proBNP >3.236 pg/mL).

Identifiers

PMID34765262
PMCPMC8577951
OpenAlexW3210968422

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.