Evidence map›Paper›PMID 34765049›Full record

ArticleDisease markers2021

Associations of Perilipin 3 with Insulin Resistance in Arab Adults with Type 2 Diabetes.

Amani Alghamdi, Dalal Z Alhotti, Shaun Sabico, Omar S Al-Attas, Nasser M Al-Daghri

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amani AlghamdiBiochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-7251-1972
Dalal Z AlhottiBiochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Shaun SabicoBiochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-5248-2350
Omar S Al-AttasBiochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Nasser M Al-DaghriBiochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0001-5472-1725
King Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe role of lipid metabolism disorders in the pathogenesis of T2DM has been recognized. Lipid droplets (LDs) are dynamic organelles that store lipids. Perilipin 3 (PLIN3) is one of the five LD coat proteins that is relatively understudied as compared to other LDs. This study is aimed at determining levels of PLIN3 among adults with varying levels of obesity and insulin resistance to determine metabolic associations of PLIN3.

resultsCirculating PLIN3 was significantly lower in the OD group [8.3 ng/mL (1.2-22.5;

conclusionCirculating PLIN3 is significantly associated with insulin resistance markers and maybe a promising candidate as a protective biomarker for T2DM.

Indexed as

Insulin ResistanceAdultBiomarkersBlood GlucoseBody Mass IndexCholesterolDiabetes Mellitus, Type 2FemaleHumansLipid MetabolismMaleMiddle AgedPerilipin-3TriglyceridesBiomarkersBlood GlucoseCholesterolPerilipin-3PLIN3 protein, humanTriglycerides

Identifiers

PMID34765049
PMCPMC8577949
OpenAlexW3209521451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.