Evidence map›Paper›PMID 34764952›Full record

ArticleFrontiers in immunology2021

Disruption of Glucocorticoid Action on CD11c

Lianghui Diao, Alexandra Maximiliane Hierweger, Agnes Wieczorek, Petra Clara Arck, Kristin Thiele

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Pregnancy-acquired memory CD4Nature communications · 2025
    Article
  3. Review
  4. Review
  5. Innate Immunity in Autoimmune Thyroid Disease during Pregnancy.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Pregnancy imparts distinct systemic adaptive immune function.American journal of reproductive immunology (New York, N.Y. : 1989) · 2022
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lianghui DiaoDivision of Experimental Feto-Maternal Medicine, Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Alexandra Maximiliane HierwegerDivision of Experimental Feto-Maternal Medicine, Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Agnes WieczorekDivision of Experimental Feto-Maternal Medicine, Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Petra Clara ArckDivision of Experimental Feto-Maternal Medicine, Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Kristin ThieleDivision of Experimental Feto-Maternal Medicine, Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Universität Hamburg · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A wealth of innate and adaptive immune cells and hormones are involved in mounting tolerance towards the fetus, a key aspect of successful reproduction. We could recently show that the specific cross talk between the pregnancy hormone progesterone and dendritic cells (DCs) is significantly engaged in the generation of CD4

Indexed as

Fetal DevelopmentAnimalsCD11 AntigensDendritic CellsFemaleFetal WeightFetusGestational AgeGlucocorticoidsHistocompatibility, Maternal-FetalImmune ToleranceMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutCD11 AntigensGlucocorticoidsItgax protein, mouseNR3C1 protein, mouseProgesteroneReceptors, Glucocorticoiddendritic cellsglucocorticoidsplacentaprogesteroneregulatory T cells (T reg)

Identifiers

PMID34764952
PMCPMC8576435
OpenAlexW3208286832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.