Evidence map›Paper›PMID 34764949›Full record

ArticleFrontiers in microbiology2021

Broad-Spectrum Inhibitor of Bacterial Polyphosphate Homeostasis Attenuates Virulence Factors and Helps Reveal Novel Physiology of

Nathan Roberge, Nolan Neville, Katya Douchant, Curtis Noordhof, Nadejda Boev, Calvin Sjaarda, Prameet M Sheth, Zongchao Jia

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  5. Two endogenousProceedings of the National Academy of Sciences of the United States of America · 2025
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  8. mSphere · 2024
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  12. Gallein and isoniazid act synergistically to attenuatebioRxiv : the preprint server for biology · 2024
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  13. Article
  14. bioRxiv : the preprint server for biology · 2023
    Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nathan RobergeDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Nolan NevilleDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Katya DouchantDepartment of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada.
Curtis NoordhofDepartment of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada.
Nadejda BoevQueen's Genomics Lab at Ongwanada (Q-GLO), Ongwanada Resource Center, Kingston, ON, Canada.
Calvin SjaardaQueen's Genomics Lab at Ongwanada (Q-GLO), Ongwanada Resource Center, Kingston, ON, Canada.
Prameet M ShethDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Zongchao JiaDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Queen's University · CAKingston Health Sciences Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acinetobacter baumannii and

Indexed as

Acinetobacter baumanniianti-virulence therapeuticgastrointestinal microbiotaKlebsiella pneumoniaepolyphosphatepolyphosphate kinase (PPK)virulence factor

Identifiers

PMID34764949
PMCPMC8576328
OpenAlexW3208792236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.