Evidence map›Paper›PMID 34764825›Full record

ReviewEngineering in life sciences2021

Separation and purification of plant terpenoids from biotransformation.

Linhao Chen, Yaru Pang, Yan Luo, Xu Cheng, Bo Lv, Chun Li

Abstract readReview
In one paragraph

Review in Engineering in life sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linhao ChenKey Laboratory of Medical Molecule Science and Pharmaceutics Engineering Ministry of Industry and Information Technology Institute of Biochemical Engineering School of Chemistry and Chemical Engineering Beijing Institute of Technology Beijing P. R. China.
Yaru PangKey Laboratory of Medical Molecule Science and Pharmaceutics Engineering Ministry of Industry and Information Technology Institute of Biochemical Engineering School of Chemistry and Chemical Engineering Beijing Institute of Technology Beijing P. R. China.
Yan LuoKey Laboratory of Medical Molecule Science and Pharmaceutics Engineering Ministry of Industry and Information Technology Institute of Biochemical Engineering School of Chemistry and Chemical Engineering Beijing Institute of Technology Beijing P. R. China.
Xu ChengKey Laboratory of Medical Molecule Science and Pharmaceutics Engineering Ministry of Industry and Information Technology Institute of Biochemical Engineering School of Chemistry and Chemical Engineering Beijing Institute of Technology Beijing P. R. China.
Bo LvKey Laboratory of Medical Molecule Science and Pharmaceutics Engineering Ministry of Industry and Information Technology Institute of Biochemical Engineering School of Chemistry and Chemical Engineering Beijing Institute of Technology Beijing P. R. China.ORCID https://orcid.org/0000-0001-7879-0741
Chun LiKey Laboratory of Medical Molecule Science and Pharmaceutics Engineering Ministry of Industry and Information Technology Institute of Biochemical Engineering School of Chemistry and Chemical Engineering Beijing Institute of Technology Beijing P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The production of plant terpenoids through biotransformation has undoubtedly become one of the research hotspots, and the continuous upgrading of the corresponding downstream technology is also particularly important. Downstream technology is the indispensable technical channel for the industrialization of plant terpenoids. How to efficiently separate high-purity products from complex microbial fermentation broths or enzyme-catalyzed reactions to achieve high separation rates, high returns and environmental friendliness has become the focus of research in recent years. This review mainly introduces the common separation methods of plant terpenoids based on biotransformation from the perspectives of engineering strain construction, unit separation technology, product properties and added value. Then, further attention was paid to the application prospects of intelligent cell factories and control in the separation of plant terpenoids. Finally, some current challenges and prospects are proposed, which provide possible directions and guidance for the separation and purification of terpenoids and even industrialization.

Indexed as

intelligent microbial cell factoriesplant terpenoidspurificationseparationsynthetic biology

Identifiers

PMID34764825
PMCPMC8576074

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.