Evidence map›Paper›PMID 34764824›Full record

ArticleAdvanced functional materials2021

High-Throughput Magnetic Actuation Platform for Evaluating the Effect of Mechanical Force on 3D Tumor Microenvironment.

Ángel Enríquez, Sarah Libring, Tyler C Field, Julian Jimenez, Taeksang Lee, Hyunsu Park, Douglas Satoski, Michael K Wendt, Sarah Calve, Adrian Buganza Tepole and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced functional materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Premetastatic niche mechanics and organotropism in breast cancer.npj biological physics and mechanics · 2025
    Review
  3. Magnetoactive,Cellular and molecular bioengineering · 2024
    Article
  4. Article
  5. Monitoring and modulation of the tumor microenvironment for enhanced cancer modeling.Experimental biology and medicine (Maywood, N.J.) · 2022
    Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ángel EnríquezWeldon School of Biomedical Engineering, Birck Nanotechnology Center, Center for Implantable Devices, Purdue University, West Lafayette, IN 47907, USA.
Sarah LibringWeldon School of Biomedical Engineering, Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA.
Tyler C FieldDepartment of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA.
Julian JimenezWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Taeksang LeeSchool of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Hyunsu ParkWeldon School of Biomedical Engineering, Birck Nanotechnology Center, Center for Implantable Devices, Purdue University, West Lafayette, IN 47907, USA.
Douglas SatoskiWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Michael K WendtPurdue Center for Cancer Research, Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
Sarah CalveWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Adrian Buganza TepoleSchool of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Luis SolorioPurdue Center for Cancer Research, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Hyowon LeeWeldon School of Biomedical Engineering, Birck Nanotechnology Center, Center for Implantable Devices, Purdue University, West Lafayette, IN 47907, USA.
Purdue University West Lafayette · US

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Engineering the Cancer MicroenvironmentR00CA198929 · NCI · PURDUE UNIVERSITY · PI SOLORIO, LUIS · 2017 to 2019
$697k
In vivo evaluation of implantable self-clearing catheter for hydrocephalusR21NS095287 · NINDS · PURDUE UNIVERSITY · PI LEE, HYOWON · 2016 to 2017
$409k
NCATS NIH HHS UL1 TR002529NCI NIH HHS R00 CA198929NINDS NIH HHS R21 NS095287
6 · The paper itself

Abstract

Accurately replicating and analyzing cellular responses to mechanical cues is vital for exploring metastatic disease progression. However, many of the existing

Indexed as

actuationbreast cancercell stretchingmechanotransductiontumor microenvironment

Identifiers

PMID34764824
PMCPMC8577425
OpenAlexW3088377134

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.