Evidence map›Paper›PMID 34764762›Full record

ArticleSaudi journal of biological sciences2021

Green synthesis of zinc nanoparticles using

Massumeh Saadatmand, Ghaidaa Raheem Lateef Al-Awsi, Abdullah D Alanazi, Asghar Sepahvand, Mojtaba Shakibaie, Saeedeh Shojaee, Rasool Mohammadi, Hossein Mahmoudvand

Open access · hybridAbstract read
In one paragraph

Article in Saudi journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. The Search for Drugs Derived from Natural Products forCurrent topics in medicinal chemistry · 2024
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  8. The effect of infection withArchives of Razi Institute · 2024
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  13. Nanoemulsion of Spiramycin against Tachyzoites ofIranian journal of public health · 2023
    Article
  14. Nanoparticles as Potent Agents for Treatment ofCurrent therapeutic research, clinical and experimental · 2023
    Review
  15. Potential effects of alpha-pinene, a monoterpene commonly found in essential oils againstJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  16. Review
  17. Therapeutic Potential and Safety of theFrontiers in cellular and infection microbiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Massumeh SaadatmandStudent Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
Ghaidaa Raheem Lateef Al-AwsiDepartment of Radiological Techniques, Al-Mustaqbal University College, Babylon, Iraq.
Abdullah D AlanaziDepartment of Biological Sciences, Faculty of Science and Humanities, Shaqra University, P.O. Box 1040, Ad-Dawadimi 11911, Saudi Arabia.
Asghar SepahvandDepartment of Medical Parasitology and Mycology, Lorestan University of Medical Sciences, Khorramabad, Iran.
Mojtaba ShakibaiePharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Saeedeh ShojaeeDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Rasool MohammadiDepartment of Biostatistics and Epidemiology, School of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran.
Hossein MahmoudvandRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Lorestan University of Medical Sciences · IRKerman University of Medical Sciences · IRShaqra University · SATehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundToday, a suitable vaccine has not yet been discovered to prevent

methodsBALB/c Mice orally administrated with ZnNPs the doses of 32.5, 75, 150 mg/kg/day for two weeks. On the 15th day, the mice were intraperitoneally infected with the Tehran strain of

resultsThe synthesized ZnNPs represent a spherical form with a size ranging from 30 to 80 nm. The results revealed that oral administration of Zn NPs at the doses of 32.5 (p < 0.001) and 75 mg/kg/day (p < 0.001) for 14 days significantly reduced the mean number and diameter of the brain tissue cysts in tested mice. No

conclusionThe obtained findings of the current investigation exhibit the significant prophylactic effects of ZnNPs against chronic toxoplasmosis in mice; so that oral administration of ZnNPs the doses 32.5, 75, 150 mg/kg reduced the parasite load and even completely controlled the infection in mice. The results show that the ZnNPs had strengthened the innate immune system which could be the reason for its strong prophylactic effects. However, further

Indexed as

In vivoLatent toxoplasmosisMicemRNANanomedicineToxoplasmosis

Identifiers

PMID34764762
PMCPMC8568829
OpenAlexW3177726690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.