ArticleJournal of ginseng research2021
Korean Red Ginseng exerts anti-inflammatory and autophagy-promoting activities in aged mice.
Article in Journal of ginseng research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 40 citations in OpenAlex.
- Korean Red Ginseng Attenuates Dysfunctions and Modulates Inflammatory and Neuroplasticity Markers in the Harmaline-Induced Model of Essential Tremor.Brain and behavior · 2026Article
- Therapeutic potential of panax ginseng-derived nanovesicles in osteoporosis through enhanced osteoblast.Journal of ginseng research · 2026Article
- Fermented Red Ginseng Restores Age-Associated Insulin Homeostasis and Gut Microbiome Balance in Mice.Biology · 2026Article
- Korean red ginseng mitigates pulmonary injury and enhances antiviral immunity in a low-dose pseudo-type SARS-CoV-2 infection model.Journal of ginseng research · 2025Article
- GRSF1 loss in THP-1 macrophages promotes senescence-associated transcription in neighboring fibroblasts.Scientific reports · 2025Article
- Homotherapy for heteropathy of chronic kidney disease and oligoasthenozoospermia through regulating SIRT1/NF-κB pathway by Shenqi pills.Frontiers in pharmacology · 2025Article
- Effects of Korean red ginseng on auditory, cognitive, and liver functions in a naturally aged mouse model.Journal of ginseng research · 2025Article
- Effect of ginseng and ginsenosides on attention deficit hyperactivity disorder: A systematic review.Journal of ginseng research · 2024Review
- Effects of enzymatic hydrolysis technology on the physicochemical properties and biological activities of American ginseng beverages.Food science & nutrition · 2024Article
- Ginseng and ginsenosides on cardiovascular and pulmonary diseases; Pharmacological potentials for the coronavirus (COVID-19).Journal of ginseng research · 2024Review
- Ginseng root-derived exosome-like nanoparticles protect skin from UV irradiation and oxidative stress by suppressing activator protein-1 signaling and limiting the generation of reactive oxygen species.Journal of ginseng research · 2024Article
- Article
- Therapeutic Potential of Natural Resources Against Endometriosis: Current Advances and Future Perspectives.Drug design, development and therapy · 2024Review
- Korean red ginseng extract prevents bone loss in an oral model of glucocorticoid induced osteoporosis in mice.Frontiers in pharmacology · 2024Article
- Anti-Inflammatory Effect ofPlants (Basel, Switzerland) · 2023Article
- Review
- Ginsenoside Re prevents 3-methyladenine-induced catagen phase acceleration by regulating Wnt/β-catenin signaling in human dermal papilla cells.Journal of ginseng research · 2023Article
- High-throughput transcriptional profiling of perturbations byJournal of pharmaceutical analysis · 2023Article
- Ginsenosides fromInternational journal of molecular sciences · 2023Review
- Antiphotoaging and Skin-Protective Activities ofPlants (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundKorean Red Ginseng (KRG) is a traditional herb that has several beneficial properties including anti-aging, anti-inflammatory, and autophagy regulatory effects. However, the mechanisms of these effects are not well understood. In this report, the underlying mechanisms of anti-inflammatory and autophagy-promoting effects were investigated in aged mice treated with KRG-water extract (WE) over a long period.
methodsThe mechanisms of anti-inflammatory and autophagy-promoting activities of KRG-WE were evaluated in kidney, lung, liver, stomach, and colon of aged mice using semi-quantitative reverse transcription polymerase chain reaction (RT-PCR), quantitative RT-PCR (qRT-PCR), and western blot analysis.
resultsKRG-WE significantly suppressed the mRNA expression levels of inflammation-related genes such as interleukin (IL)-1β, IL-8, tumor necrosis factor (TNF)-α, monocyte chemoattractant protein-1
conclusionThe results suggest that KRG can suppress inflammatory responses and recover autophagy activity in aged mice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.