Evidence map›Paper›PMID 34764717›Full record

ReviewJournal of ginseng research2021

Yan Wan, Jing Wang, Jin-Feng Xu, Fei Tang, Lu Chen, Yu-Zhu Tan, Chao-Long Rao, Hui Ao, Cheng Peng

Abstract readReview
In one paragraph

Review in Journal of ginseng research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Article
  2. Role of (pro) renin receptor in adriamycin-induced cardiomyopathy.International journal of cardiology. Heart & vasculature · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Exploration of the role ofFrontiers in pharmacology · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan WanState Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jing WangState Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jin-Feng XuState Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Fei TangState Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Lu ChenState Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yu-Zhu TanState Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Chao-Long RaoCollege of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Hui AoState Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Cheng PengState Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemotherapy-induced side effects affect the quality of life and efficacy of treatment of cancer patients. Current approaches for treating the side effects of chemotherapy are poorly effective and may cause numerous harmful side effects. Therefore, developing new and effective drugs derived from natural non-toxic compounds for the treatment of chemotherapy-induced side effects is necessary. Experiments in vivo and in vitro indicate that

Indexed as

5-FU, 5-fluorouracilADM, AdriamycinALT, alanine aminotransferaseAMO, Atractylodes macrocephala volatile oilAMPK, AMP-activated protein kinaseARE, antioxidant response elementAST, aspartate aminotransferaseBMNC, bone marrow nucleated cellsChemotherapyCIA, chemotherapy-induced hair lossCK, compound KCP, cisplatinCY, cyclophosphamideCYP2E1, Cytochrome P450 E1DAC, doses of docetaxel, doxorubicin as well as cyclophosphamideeRG, 50% ethanol-extracted RGERG, enzyme-treated eRGERK, extracellular signal-regulated kinasesFBG, fermented black ginsengFRGE, fermented red ginseng extractFRG, probiotic-fermented eRGGinsenosidesGM-CSF, granulocyte macrophage colony-stimulating factorHEI-OC1, House Ear Institute-Organ of Corti 1HO-1, heme oxygenase-1HSPCS, haematopoietic stem and progenitor cellsIL, interleukinJNK, c-jun N-terminal kinaseKG-KH, the mixture of ginsenosides Rk3 and Rh4LLC-PK1, porcine renal proximal epithelial tubularLSK, Lin−Sca-1+c-kit+MAPK, mitogen-activated protein kinaseMDA, malonaldehydeMechanismMEK, mitogen activated protein kinaseMKK4, mitogen activated protein kinase kinase 4mTOR, mammalian target of rapamycinNF-κB, nuclear factor-kappa B p65NQO, NAD (P) H quinone oxidoreductaseNrf2, nuclear factor erythroid related factor 2PGPGFR, PG flowerPGLF, PG leafPG, Panax ginsengPGRT, PG rootPGSD, PG seedsPGSM, PG stemPGS, PG total saponinsPharmacological effectsPI3K, phosphatidylinositol 3-kinasePPD, protopanaxadiolPPT, protopanaxatriolRGE, red ginseng extractRG, red ginsengROS, reactive oxygen speciesSide effectsSREBP-1, sterol regulatory element binding protein 1TNF-α, tumor necrosis factor-αwRG, water-extracted RG

Identifiers

PMID34764717
PMCPMC8569258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.