Evidence map›Paper›PMID 34764704›Full record

ReviewHepatic medicine : evidence and research2021

Identifying Patients at High Risk of Developing Non-Cirrhotic Portal Hypertension.

Stefania Gioia, Oliviero Riggio, Silvia Nardelli, Giulia d'Amati, Lorenzo Ridola

Abstract readReview
In one paragraph

Review in Hepatic medicine : evidence and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Role of Gut-Derived Endotoxins in Porto-Sinusoidal Vascular Disorder: Comparison Between patients with and without portal hypertension.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefania GioiaDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Oliviero RiggioDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Silvia NardelliDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Giulia d'AmatiDepartment of Radiological, Oncological, and Pathological Sciences, Sapienza University of Rome, Rome, Italy.
Lorenzo RidolaDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The term porto-sinusoidal vascular disease (PSVD) has been recently proposed to replace the term idiopathic non-cirrhotic portal hypertension (INCPH) to describe patients with or without signs of portal hypertension and typical histological lesions involving the portal venules or sinusoids in the absence of cirrhosis. According to the new definition, the presence of known causes of liver disease as well as of portal vein thrombosis does not rule out PSVD. Therefore, the patients in whom the diagnosis of PSVD is possible are much more than the patients strictly fulfilling the diagnostic criteria for INCPH. In this setting, the clinical challenge for the hepatologist is to identify patients at risk of developing PSVD and to indicate liver biopsy to confirm the diagnosis. We describe some possible scenarios in which PSVD should always be suspected, and we provide some tools useful to reach the diagnosis of PSVD.

Indexed as

idiopathic non-cirrhotic portal hypertensionportal hypertensionportal vein thrombosisporto-sinusoidal vascular liver disease

Identifiers

PMID34764704
PMCPMC8572743

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.