Evidence map›Paper›PMID 34764504›Full record

ArticleIndian journal of anaesthesia2021

Major neurological complications following central neuraxial blockade - A multicentre pilot study in Aurangabad city (MGMA CNB Study).

Sadhana Sudhir Kulkarni, Deepak Narayan Tayade, Mukund Kachru Parchandekar, Prabha Pandurang Nayak, Vasanti Prabhakar Kelkar, Prashant Jangonda Pachore

Open access · diamondAbstract read
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Article in Indian journal of anaesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sadhana Sudhir KulkarniDepartment of Emergency Medicine, MGM Medical College and Hospital, Aurangabad, Maharashtra, India.
Deepak Narayan TayadeDepartment of Community Medicine, MGM Medical College and Hospital, Aurangabad, Maharashtra, India.
Mukund Kachru ParchandekarDepartment of Anaesthesiology, Govt. Medical College, Aurangabad, Maharashtra, India.
Prabha Pandurang NayakDepartment of Anaesthesiology, MGM Medical College and Hospital, Aurangabad, Maharashtra, India.
Vasanti Prabhakar KelkarDepartment of Anaesthesiology, MGM Medical College and Hospital, Aurangabad, Maharashtra, India.
Prashant Jangonda PachoreDepartment of Anaesthesiology, Govt. Medical College, Aurangabad, Maharashtra, India.
Mahatma Gandhi Mission Medical College and Hospital · INGovernment Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsIncidence of major neurological complications following central neuraxial blockade (CNB) in India is not known. This information is essential for explaining risk preoperatively to patients and for medico-legal purposes. This study was undertaken to assess feasibility (recruitment process, protocol adherence, resources mobilisation, data management and evaluation of scientific outcome) for planning multicentric studies on major neurological complications following CNB at state/national level.

methodsThis was a hospital-based, multicentre pilot study, with cross-sectional and follow-up components. Patients receiving CNB either perioperatively or during acute/chronic pain management were included in the study. Thirty-six randomly selected tertiary and nontertiary care institutes were included. Details of demographic information, CNB procedure and major neurological complications were collected anonymously via online tools. Feedback about study feasibility was collected from participating anaesthesiologists and study team.

resultsSelected institutes continued participation throughout study period. About 99.98% of eligible patients were enroled. Complete data collection of 8053 patients and analysis was possible. Regular reminders from study coordinators helped to optimise data collection. Tertiary care institutes contributed to 74.50% of data. About 64.96% patients were females. Spinal anaesthesia was the most frequently used neuraxial block (93.41%). Bupivacaine and adjuvant were used in 95.53% and 16.5% patients, respectively. Two patients developed cardiac arrest and cause-effect relationship with CNB was established. Participants' recruitment, protocol adherence, resources mobilisation, data management and evaluation of scientific outcomes were feasible.

conclusionA multicentre state/nationwide study can be conducted based on this first-of-its-kind pilot study in India.

Indexed as

Complicationsfeasibility studymulticentre studyneuraxial anaesthesianeurological manifestationspilot study

Identifiers

PMID34764504
PMCPMC8577715
OpenAlexW3204031119

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.