Evidence map›Paper›PMID 34764278›Full record

ArticleNature communications2021

Insulin-activated store-operated Ca

Ji-Hee Kim, Kyu-Hee Hwang, Bao T N Dang, Minseob Eom, In Deok Kong, Yousang Gwack, Seyoung Yu, Heon Yung Gee, Lutz Birnbaumer, Kyu-Sang Park and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. EndothelialInternational journal of medical sciences · 2025
    Article
  3. Differential expression of ORAI channels and STIM proteins in renal cell carcinoma subtypes: implications for metastasis and therapeutic targeting.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2025
    Article
  4. Article
  5. Non-voltage-gated CaAmerican journal of physiology. Renal physiology · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Store-operated CaExperimental biology and medicine (Maywood, N.J.) · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Enhanced Orai1-mediated store-operated CaThe Journal of biological chemistry · 2022
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Ji-Hee KimDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
Kyu-Hee HwangDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
Bao T N DangDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
Minseob EomDepartment of Pathology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
In Deok KongDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
Yousang GwackDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.ORCID http://orcid.org/0000-0002-2821-9245
Seyoung YuDepartment of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.
Heon Yung GeeDepartment of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-8741-6177
Lutz BirnbaumerNeurobiology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA.
Kyu-Sang ParkDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.ORCID http://orcid.org/0000-0003-0322-9807
Seung-Kuy ChaDepartment of Physiology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea. skcha@yonsei.ac.kr.ORCID http://orcid.org/0000-0003-3201-7950
Yonsei University · KRPontificia Universidad Católica Argentina · ARUniversity of California, Los Angeles · US

Funding

Transmembrane Signaling Mechanisms Involving TRP ChannelsZ01ES101684 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI BIRNBAUMER, LUTZ · 2003 to 2008
$2.1M
Intramural NIH HHS Z01 ES101684
6 · The paper itself

Abstract

Podocyte, the gatekeeper of the glomerular filtration barrier, is a primary target for growth factor and Ca

Indexed as

AnimalsBiotinylationBlotting, WesternCalciumFluorescent Antibody TechniqueMaleMiceMice, KnockoutMicroscopy, Electron, TransmissionORAI1 ProteinPodocytesProteinuriaReal-Time Polymerase Chain ReactionCalciumORAI1 ProteinOrai1 protein, mouse

Identifiers

PMID34764278
PMCPMC8586150
OpenAlexW3212362093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.