Evidence map›Paper›PMID 34764115›Full record

ArticleBMJ case reports2021

Recurrent giant cell tumour of the distal ulna after en bloc resection with preoperative denosumab use.

Nasa Fujihara, Shunsuke Hamada, Masahiro Yoshida, Satoshi Tsukushi

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nasa FujiharaOrthopaedic, Aichi Cancer Center, Nagoya, Aichi, Japan nfujihara@aichi-cc.jp.ORCID http://orcid.org/0000-0002-4197-0586
Shunsuke HamadaOrthopaedic, Aichi Cancer Center, Nagoya, Aichi, Japan.
Masahiro YoshidaOrthopaedic, Aichi Cancer Center, Nagoya, Aichi, Japan.
Satoshi TsukushiOrthopaedic, Aichi Cancer Center, Nagoya, Aichi, Japan.
Aichi Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, denosumab has been used to treat giant cell tumour of bone (GCTB) not only in cases where surgery is complicated but also preoperatively to decrease the preoperative grade or to facilitate surgery for Campanacci grade II and III cases. However, there are no clear protocols regarding the preoperative use of denosumab before en bloc resection. There are a few reports of recurrent cases after en bloc resection; however, the association with the use of denosumab is unknown. We present the clinical, radiological and histopathological findings of a case of Campanacci grade III GCTB at the distal end of the ulna, which resulted in soft tissue recurrence after en bloc resection with the preoperative use of denosumab.

Indexed as

Bone Density Conservation AgentsBone NeoplasmsGiant Cell Tumor of BoneDenosumabHumansNeoplasm Recurrence, LocalRetrospective StudiesUlnaBone Density Conservation AgentsDenosumabmusculoskeletal and joint disordersorthopaedic and trauma surgeryorthopaedicsprosthesis failure

Identifiers

PMID34764115
PMCPMC8586889
OpenAlexW3211394307

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.