Evidence map›Paper›PMID 34763417›Full record

ArticleACS chemical biology2021

Structure and Function of a Dual Reductase-Dehydratase Enzyme System Involved in

Jonathan A Clinger, Yinan Zhang, Yang Liu, Mitchell D Miller, Ronnie E Hall, Steven G Van Lanen, George N Phillips, Jon S Thorson, Sherif I Elshahawi

Abstract read
In one paragraph

Article in ACS chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Chemistry and biology of marine-derived Trichoderma metabolites.Natural products and bioprospecting · 2024
    Review
  6. Promiscuous Enzymes for Residue-Specific Peptide and Protein Late-Stage Functionalization.Chembiochem : a European journal of chemical biology · 2023
    Review
  7. Review
  8. Article
  9. Metabolic Engineering ofMicroorganisms · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jonathan A ClingerDepartment of Biosciences, Rice University, Houston, Texas 77005, United States.ORCID 0000-0002-4864-1427
Yinan ZhangDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.ORCID 0000-0002-0362-1473
Yang LiuDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.
Mitchell D MillerDepartment of Biosciences, Rice University, Houston, Texas 77005, United States.ORCID 0000-0003-1626-4943
Ronnie E HallDepartment of Biosciences, Rice University, Houston, Texas 77005, United States.
Steven G Van LanenDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.ORCID 0000-0003-1539-2732
George N PhillipsDepartment of Biosciences, Rice University, Houston, Texas 77005, United States.
Jon S ThorsonDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.ORCID 0000-0002-7148-0721
Sherif I ElshahawiDepartment of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, California 92618, United States.ORCID 0000-0003-1879-1552

Funding

User Training & OutreachP30GM138396 · NIGMS · UCHICAGO ARGONNE, LLC · PI JANET L. SMITH · 2020 to 2026
$34.3M
Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
Understanding the role of anti-apolipoprotein A-I antibodies in atherosclerotic cardiovascular diseaseP20GM130456 · NIGMS · UNIVERSITY OF KENTUCKY · PI M. Ashfaqul Alam · 2020 to 2026
$18.7M
Kentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3M
HOUSTON AREA MOLECULAR BIOPHYSICS TRAINING PROGRAMT32GM008280 · NIGMS · RICE UNIVERSITY · PI WENSEL, THEODORE G · 1988 to 2023
$8.0M
Enzyme Discovery for Natural Product BiosynthesisU01GM098248 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PHILLIPS, GEORGE NEAL · 2011 to 2015
$2.8M
Studies to understand and exploit 10-membered enediyne biosynthesisR01CA217255 · NCI · UNIVERSITY OF KENTUCKY · PI PHILLIPS, GEORGE NEAL, THORSON, JON SCOTT · 2017 to 2021
$2.6M
Platform technologies for understanding and exploiting methylationR01GM115261 · NIGMS · UNIVERSITY OF KENTUCKY · PI PHILLIPS, GEORGE NEAL, THORSON, JON SCOTT · 2016 to 2019
$2.2M
Bruker AVANCE NEO 600 MHz High-Performance Digital NMR SpectrometerS10OD028690 · OD · UNIVERSITY OF KENTUCKY · PI GARNEAU-TSODIKOVA, SYLVIE · 2020 to 2020
$1.4M
NCATS NIH HHS UL1 TR000117NCATS NIH HHS UL1 TR001998NCI NIH HHS R01 CA217255NIGMS NIH HHS P20 GM130456NIGMS NIH HHS P30 GM138396NIGMS NIH HHS R01 GM115261NIGMS NIH HHS T32 GM008280NIGMS NIH HHS U01 GM098248NIH HHS S10 OD028690
6 · The paper itself

Abstract

We report the identification of the

Indexed as

Amino Acid SequenceArginineAspartic AcidBiosynthetic PathwaysCatalysisCrystallography, X-RayEscherichia coliHydro-LyasesModels, MolecularOxidoreductasesProtein BindingStreptomycesStructure-Activity RelationshipTerphenyl CompoundsArginineAspartic AcidHydro-LyasesOxidoreductasesTerphenyl Compounds

Identifiers

PMID34763417
PMCPMC8751757

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.