ArticleInternational journal of radiation oncology, biology, physics2022
Treatment Planning System for Electron FLASH Radiation Therapy: Open-Source for Clinical Implementation.
Article in International journal of radiation oncology, biology, physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Comprehensive characterization and validation of a fast-resolving (1000 Hz) plastic scintillator for ultra-high dose rate electron dosimetry.Medical physics · 2025Article
- Characterization of a shielded beam current transformer for ultra-high dose rate (FLASH) electron beam monitoring and dose reporting.Medical physics · 2025Article
- FLASH radiotherapy combined with immunotherapy: From biological mechanisms to blockbuster therapeutics.Translational oncology · 2025Review
- A methodology for optimizing treatment head angle arrangement for multi-angle FLASH intensity modulated radiation therapy platforms.Frontiers in oncology · 2025Article
- Commissioning an ultra-high-dose-rate electron linac with end-to-end tests.Physics in medicine and biology · 2024Article
- Electron beam response corrections for an ultra-high-dose-rate capable diode dosimeter.Medical physics · 2024Article
- First Monte Carlo beam model for ultra-high dose rate radiotherapy with a compact electron LINAC.Medical physics · 2024Article
- Characterization of a diode dosimeter for UHDR FLASH radiotherapy.Medical physics · 2023Article
- Framework for Quality Assurance of Ultrahigh Dose Rate Clinical Trials Investigating FLASH Effects and Current Technology Gaps.International journal of radiation oncology, biology, physics · 2023Review
- FLASH radiotherapy: A promising new method for radiotherapy.Oncology letters · 2022Review
- A potential revolution in cancer treatment: A topical review of FLASH radiotherapy.Journal of applied clinical medical physics · 2022Review
- Failure Mode and Effects Analysis for Experimental Use of FLASH on a Clinical Accelerator.Practical radiation oncologyArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
purposeTo present a Monte Carlo (MC) beam model and its implementation in a clinical treatment planning system (TPS, Varian Eclipse) for a modified ultrahigh dose-rate electron FLASH radiation therapy (eFLASH-RT) linear accelerator (LINAC) using clinical accessories and geometry. METHODS AND MATERIALS: The gantry head without scattering foils or targets, representative of the LINAC modifications, was modeled in the Geant4-based GAMOS MC toolkit. The energy spectrum (σ
resultsThe eFLASH beam model agreed best with measurements at σ
conclusionsTo our knowledge, this is the first functional beam model commissioned in a clinical TPS for eFLASH-RT enabling planning and evaluation with minimal deviation from the Conv-RT workflow. It facilitates the clinical translation because eFLASH-RT and Conv-RT plan quality were comparable for a human patient involving complex geometries and tissue heterogeneity. The methods can be expanded to model other eFLASH irradiators with different beam characteristics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.