Evidence map›Paper›PMID 34762595›Full record

ArticleDiabetes care2021

Oral Glucose Tolerance Test Predicts Episodic Memory Decline: A 10-Year Population-Based Follow-up Study.

Sini Toppala, Laura L Ekblad, Matti Viitanen, Juha O Rinne, Antti Jula

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sini ToppalaTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
Laura L EkbladTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland llekbl@utu.fi.ORCID 0000-0002-5863-8088
Matti ViitanenCity of Turku, Welfare Division, Turku City Hospital, Turku, Finland.
Juha O RinneTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
Antti JulaNational Institute for Health and Welfare, Turku, Finland.
University of Turku · FIFinnish Institute for Health and Welfare · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine if the 2-h value of an oral glucose tolerance test (OGTT) can predict cognitive decline. RESEARCH DESIGN AND

methodsThis study is based on a subpopulation of the Finnish population-based Health 2000 Survey and its follow-up, the Health 2011 study. Altogether, 961 individuals aged 45-74 (mean 55.6 years; 55.8% women) underwent OGTT in 2001-2002. Categorical verbal fluency, word-list learning, and word-list delayed recall were tested at baseline and at follow-up in 2011. Statistical analyses were performed with multivariable linear models adjusted for previously reported risk factors for cognitive decline.

resultsA higher 2-h glucose value in the OGTT at baseline predicted worse performance (slope: -0.08;

conclusionsOur results indicate that higher 2-h glucose values in the OGTT predict a decline in episodic memory after 10 years.

Indexed as

Cognitive DysfunctionMemory, EpisodicAgedFemaleFollow-Up StudiesGlucose Tolerance TestHumansMaleMiddle AgedRisk Factors

Identifiers

PMID34762595
PMCPMC8740941
OpenAlexW3195042876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.