Evidence map›Paper›PMID 34762492›Full record

Observational studyThe British journal of radiology2022

PET/MR in recurrent glioblastoma patients treated with regorafenib: [

Giuseppe Lombardi, Alessandro Spimpolo, Sara Berti, Cristina Campi, Maria Giulia Anglani, Rossella Simeone, Laura Evangelista, Francesco Causin, Giovanni Zorzi, Giancarlo Gorgoni and 4 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. [European journal of nuclear medicine and molecular imaging · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Radiation oncology (London, England) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Giuseppe LombardiDepartment of Oncology, Oncology 1, Veneto Institute of Oncology - IRCCS, Padua, Italy.
Alessandro SpimpoloNuclear Medicine Unit, Department of Medicine - DIMED, Padua University Hospital, Padua, Italy.
Sara BertiNuclear Medicine Unit, Department of Medicine - DIMED, Padua University Hospital, Padua, Italy.
Cristina CampiDepartment of Mathematics, University of Genoa, Genoa, Italy.
Maria Giulia AnglaniNeuroradiology Unit, Azienda Ospedaliera di Padova, Padua, Italy.
Rossella SimeoneNuclear Medicine Unit, Department of Medicine - DIMED, Padua University Hospital, Padua, Italy.
Laura EvangelistaNuclear Medicine Unit, Department of Medicine - DIMED, Padua University Hospital, Padua, Italy.
Francesco CausinNeuroradiology Unit, Azienda Ospedaliera di Padova, Padua, Italy.
Giovanni ZorziDepartment of Neurosciences (DNS), University of Padua, Padua, Italy.
Giancarlo GorgoniRadiopharmacy, Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy.
Mario CacceseDepartment of Oncology, Oncology 1, Veneto Institute of Oncology - IRCCS, Padua, Italy.
Marta PadovanDepartment of Oncology, Oncology 1, Veneto Institute of Oncology - IRCCS, Padua, Italy.
Vittorina ZagonelDepartment of Oncology, Oncology 1, Veneto Institute of Oncology - IRCCS, Padua, Italy.
Diego CecchinNuclear Medicine Unit, Department of Medicine - DIMED, Padua University Hospital, Padua, Italy.ORCID 0000-0001-7956-1924
University of Padua · ITIstituto Oncologico Veneto · ITAzienda Ospedale - Università Padova · ITOspedale Sacro Cuore Don Calabria · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe use of regorafenib in recurrent glioblastoma patients has been recently approved by the Italian Medicines Agency (AIFA) and added to the National Comprehensive Cancer Network (NCCN) 2020 guidelines as a preferred regimen. Given its complex effects at the molecular level, the most appropriate imaging tools to assess early response to treatment is still a matter of debate. Diffusion-weighted imaging and O-(2-

methodsWe retrospectively reviewed 16 consecutive GBM patients who underwent [

resultsPercentage difference in FET volumes correlates with the corresponding percentage difference in ADC (

conclusionIn recurrent glioblastoma patients treated with regorafenib, [ ADVANCES IN KNOWLEDGE: Simultaneous evaluation of [

Indexed as

AdultAgedAntineoplastic AgentsBrain NeoplasmsDiffusion Magnetic Resonance ImagingFemaleFluorodeoxyglucose F18GlioblastomaHumansMaleMiddle AgedNeoplasm Recurrence, LocalPhenylurea CompoundsPositron-Emission TomographyPyridinesRadiopharmaceuticalsAntineoplastic AgentsFluorodeoxyglucose F18Phenylurea CompoundsPyridinesRadiopharmaceuticalsregorafenib

Identifiers

PMID34762492
PMCPMC8722234
OpenAlexW3213016178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.