Evidence map›Paper›PMID 34762476›Full record

ArticleScience (New York, N.Y.)2021

Symmetry breaking in the female germline cyst.

D Nashchekin, L Busby, M Jakobs, I Squires, D St Johnston

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. AnbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Myosin VI is expressed in developing ovarian follicles inFrontiers in cell and developmental biology · 2025
    Article
  6. EB-SUN, a new microtubule plus-end tracking protein inMolecular biology of the cell · 2024
    Article
  7. EB-SUN, a New Microtubule Plus-End Tracking Protein inbioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Article
  10. Positioning centrioles and centrosomes.The Journal of cell biology · 2024
    Review
  11. Article
  12. Review
  13. The dynamic duo of microtubule polymerase Mini spindles/XMAP215 and cytoplasmic dynein is essential for maintainingProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Article
  15. Genetic and Epigenetic Regulation ofJournal of developmental biology · 2023
    Review
  16. bioRxiv : the preprint server for biology · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

D NashchekinThe Gurdon Institute and the Department of Genetics, University of Cambridge, Cambridge CB2 1QN, UK.ORCID 0000-0001-7372-0752
L BusbyThe Gurdon Institute and the Department of Genetics, University of Cambridge, Cambridge CB2 1QN, UK.ORCID 0000-0003-0705-1364
M JakobsThe Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK.ORCID 0000-0002-0879-7937
I SquiresThe Gurdon Institute and the Department of Genetics, University of Cambridge, Cambridge CB2 1QN, UK.ORCID 0000-0002-3424-6354
D St JohnstonThe Gurdon Institute and the Department of Genetics, University of Cambridge, Cambridge CB2 1QN, UK.ORCID 0000-0001-5582-3301

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Biotechnology and Biological Sciences Research Council BB/R001618/1Cancer Research UK A14492NIH HHS P40 OD018537Wellcome Trust 080007Wellcome Trust 092096Wellcome Trust 109145Wellcome Trust 203144Wellcome Trust 207496Wellcome Trust 207496/Z/17/Z
6 · The paper itself

Abstract

In mammals and flies, only one cell in a multicellular female germline cyst becomes an oocyte, but how symmetry is broken to select the oocyte is unknown. Here, we show that the microtubule (MT) minus end-stabilizing protein Patronin/CAMSAP marks the future

Indexed as

AnimalsAnisotropyDrosophila melanogasterDrosophila ProteinsDyneinsFemaleGerm CellsMicrofilament ProteinsMicrotubule-Associated ProteinsMicrotubule-Organizing CenterMicrotubulesOocytesOrganellesDrosophila ProteinsDyneinsMicrofilament ProteinsMicrotubule-Associated Proteinspatronin protein, Drosophilashot protein, Drosophila

Identifiers

PMID34762476
PMCPMC7612008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.