Evidence map›Paper›PMID 34762468›Full record

ArticleScience (New York, N.Y.)2021

The genetic and epigenetic landscape of the

Matthew Naish, Michael Alonge, Piotr Wlodzimierz, Andrew J Tock, Bradley W Abramson, Anna Schmücker, Terezie Mandáková, Bhagyshree Jamge, Christophe Lambing, Pallas Kuo and 14 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 266 papers.

0numbers the graph read from it
0cells of the map it votes in
266citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

266 citing papers in PubMed.

  1. Article
  2. Near-complete genomes for nine haplochromine cichlid fishes reveal a novel centromeric satellite structure organised around a pair of inverted elements.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
    Article
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  15. Review
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  20. Article

206 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors.

Matthew Naish *Department of Plant Sciences, Downing Street, University of Cambridge, Cambridge CB2 3EA, UK.ORCID 0000-0002-8977-1295
Michael Alonge *Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-3692-1819
Piotr Wlodzimierz *Department of Plant Sciences, Downing Street, University of Cambridge, Cambridge CB2 3EA, UK.ORCID 0000-0003-1040-7878
Andrew J TockDepartment of Plant Sciences, Downing Street, University of Cambridge, Cambridge CB2 3EA, UK.ORCID 0000-0002-6590-8314
Bradley W AbramsonThe Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID 0000-0003-0888-3648
Anna SchmückerGregor Mendel Institute (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Dr. Bohr-Gasse 3, 1030 Vienna, Austria.
Terezie MandákováCentral European Institute of Technology (CEITEC), Masaryk University, Kamenice 5, Brno 625 00, Czech Republic.ORCID 0000-0001-6485-0563
Bhagyshree JamgeGregor Mendel Institute (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Dr. Bohr-Gasse 3, 1030 Vienna, Austria.ORCID 0000-0003-3722-1352
Christophe LambingDepartment of Plant Sciences, Downing Street, University of Cambridge, Cambridge CB2 3EA, UK.ORCID 0000-0001-5218-4217
Pallas KuoDepartment of Plant Sciences, Downing Street, University of Cambridge, Cambridge CB2 3EA, UK.ORCID 0000-0001-5435-2026
Natasha YelinaDepartment of Plant Sciences, Downing Street, University of Cambridge, Cambridge CB2 3EA, UK.
Nolan HartwickThe Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID 0000-0001-7916-7791
Kelly ColtThe Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID 0000-0001-8913-4678
Lisa M SmithSchool of Biosciences and Institute for Sustainable Food, University of Sheffield, Sheffield S10 2TN, UK.ORCID 0000-0003-2364-8187
Jurriaan TonSchool of Biosciences and Institute for Sustainable Food, University of Sheffield, Sheffield S10 2TN, UK.ORCID 0000-0002-8512-2802
Tetsuji KakutaniDepartment of Biological Sciences, University of Tokyo, Tokyo, Japan.ORCID 0000-0002-6137-4474
Robert A MartienssenHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.ORCID 0000-0003-1285-9608
Korbinian SchneebergerFaculty of Biology, LMU Munich, Großhaderner Str. 2, 82152 Planegg-Martinsried, Germany.
Martin A LysakCentral European Institute of Technology (CEITEC), Masaryk University, Kamenice 5, Brno 625 00, Czech Republic.ORCID 0000-0003-0318-4194
Frédéric BergerGregor Mendel Institute (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Dr. Bohr-Gasse 3, 1030 Vienna, Austria.ORCID 0000-0002-3609-8260
Alexandros BousiosSchool of Life Sciences, University of Sussex, Brighton BN1 9RH, UK.ORCID 0000-0002-8005-6949
Todd P MichaelThe Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID 0000-0001-6272-2875
Michael C SchatzDepartment of Computer Science, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-4118-4446
Ian R HendersonDepartment of Plant Sciences, Downing Street, University of Cambridge, Cambridge CB2 3EA, UK.

Funding

Single-Cell Biology Shared ResourceP30CA045508 · NCI · COLD SPRING HARBOR LABORATORY · PI John Edward Moses · 1987 to 2026
$118.9M
Transposons, RNA Interference and HeterochromatinR01GM067014 · NIGMS · COLD SPRING HARBOR LABORATORY · PI MARTIENSSEN, ROBERT A · 2003 to 2016
$4.1M
Graphical Processing Units and a Large-Memory Compute Node for Applications in Genomics, Neuroscience, and Structural BiologyS10OD028632 · OD · COLD SPRING HARBOR LABORATORY · PI SIEPEL, ADAM CHARLES · 2020 to 2020
$437k
Austrian Science Fund FWF P 26887Austrian Science Fund FWF P 28320Austrian Science Fund FWF P 30802Austrian Science Fund FWF P 32054Austrian Science Fund FWF TAI 304Biotechnology and Biological Sciences Research Council BB/N007557/1NCI NIH HHS P30 CA045508NIGMS NIH HHS R01 GM067014NIH HHS S10 OD028632
6 · The paper itself

Abstract

Centromeres attach chromosomes to spindle microtubules during cell division and, despite this conserved role, show paradoxically rapid evolution and are typified by complex repeats. We used long-read sequencing to generate the Col-CEN

Indexed as

Epigenesis, GeneticArabidopsisCentromereChromosomes, PlantDNA MethylationDNA, SatelliteEvolution, MolecularGenome, PlantHistonesMeiosisRecombination, GeneticRetroelementsSequence Analysis, DNADNA, SatelliteHistonesRetroelements

Identifiers

PMID34762468
PMCPMC10164409

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.