Evidence map›Paper›PMID 34762278›Full record

ArticleInternational ophthalmology2022

Detection of COVID-19 in tears of ICU-admitted patients with SARS-CoV-2 infection.

Seyed Hashem Daryabari, Atieh Asadollah, Farhad Adhami Moghadam, Ruhollah Dorostkar, Ali Bahramifar, Hossein Aghamollaei

Erratum issuedAbstract read
In one paragraph

Article in International ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. COVID-19 pandemic and ophthalmology: insights from the IVORC Academic Foundation.Medical hypothesis, discovery & innovation ophthalmology journal · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Seyed Hashem DaryabariBaghiatollah University of Medical Sciences, Tehran, Islamic Republic of Iran. shdarya50@yahoo.com.
Atieh AsadollahBaghiatollah University of Medical Sciences, Tehran, Islamic Republic of Iran.
Farhad Adhami MoghadamBaghiatollah University of Medical Sciences, Tehran, Islamic Republic of Iran.
Ruhollah DorostkarBaghiatollah University of Medical Sciences, Tehran, Islamic Republic of Iran.
Ali BahramifarBaghiatollah University of Medical Sciences, Tehran, Islamic Republic of Iran.
Hossein AghamollaeiBaghiatollah University of Medical Sciences, Tehran, Islamic Republic of Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUpon the outbreak of 2019, novel coronavirus (COVID-19) pandemic confirmed the cases surpassed 20 million. Despite a few reports identified the association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with ocular manifestations, it may assess the ocular symptoms of patients with the COVID-19 by ophthalmologists facilitate the diagnosis and prevent transmission.

methodsA total of 60 patients with the COVID-19 admitted to Baghiatallah hospital from March 2020 to May 2020 were retrospectively reviewed and analyzed for the ocular manifestations, blood tests, and reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV-2 using nasopharyngeal and conjunctival swabs.

resultsAmong 60 included patients with clinically confirmed COVID-19, the median age 58.36 years (IQR: 30-88 years), 27 (45%) were male. Furthermore, 29 (48%) and 5 (8%) patients yielded positive for SARS-CoV-2 on RT-PCR from nasopharyngeal swabs and conjunctival specimens, respectively. Among 60 patients, 10 (16%) and 3 (5%), respectively, had the ocular manifestations and positive results for SARS-CoV-2 on RT-PCR from conjunctival and nasopharyngeal swabs.

conclusionAlthough the positive rate of tear RT-PCR rate is not noticeable as nasopharyngeal swabs yet, COVID-19 transmission through the eyes is biologically plausible.

Indexed as

COVID-19ConjunctivaHumansIntensive Care UnitsMaleMiddle AgedRetrospective StudiesRNA, ViralSARS-CoV-2TearsRNA, ViralCOVID-19Nasopharyngeal RT-PCROcular manifestationTear RT-PCR

Identifiers

PMID34762278
PMCPMC8581600

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.