Evidence map›Paper›PMID 34762221›Full record

ArticleMycopathologia2022

Domestic Birds as Source of Cryptococcus deuterogattii (AFLP6/VGII): Potential Risk for Cryptococcosis.

Nathan P Siqueira, Olívia C Favalessa, Fernanda H Maruyama, Valéria Dutra, Luciano Nakazato, Ferry Hagen, Rosane C Hahn

Open access · hybridAbstract read
In one paragraph

Article in Mycopathologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Frontiers in medicine · 2026
    Article
  4. Article
  5. What Do We Know AboutJournal of fungi (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Fungal diversity isolated from the gastrointestinal tract of psittacines kept as pets: a potential public health risk?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  8. Disseminated Skeletal Cryptococcosis: A Case Report.Journal of orthopaedic case reports · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Emerging Animal-Associated Fungal Diseases.Journal of fungi (Basel, Switzerland) · 2022
    Review
  13. Search forJournal of fungi (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Nathan P SiqueiraMedical Mycology/Research Laboratory, Medicine School, Federal University of Mato Grosso (UFMT), Fernando Corrêa Avenue, 2387, Boa Esperança, Cuiabá, 78060-900, Brazil.ORCID http://orcid.org/0000-0003-0745-5895
Olívia C FavalessaMedical Mycology/Research Laboratory, Medicine School, Federal University of Mato Grosso (UFMT), Fernando Corrêa Avenue, 2387, Boa Esperança, Cuiabá, 78060-900, Brazil.ORCID http://orcid.org/0000-0002-1559-5217
Fernanda H MaruyamaVeterinary Microbiology and Molecular Biology Laboratory, Federal University of Mato Grosso (UFMT), Cuiabá, Brazil.ORCID http://orcid.org/0000-0002-1847-7574
Valéria DutraVeterinary Microbiology and Molecular Biology Laboratory, Federal University of Mato Grosso (UFMT), Cuiabá, Brazil.ORCID http://orcid.org/0000-0002-6630-2293
Luciano NakazatoVeterinary Microbiology and Molecular Biology Laboratory, Federal University of Mato Grosso (UFMT), Cuiabá, Brazil.ORCID http://orcid.org/0000-0002-1244-0690
Ferry HagenDepartment of Medical Mycology, Westerdijk Fungal Biodiversity Institute (WI-KNAW), Uppsalalaan 8, 3584CT, Utrecht, The Netherlands. f.hagen@wi.knaw.nl.ORCID http://orcid.org/0000-0002-5622-1916
Rosane C HahnMedical Mycology/Research Laboratory, Medicine School, Federal University of Mato Grosso (UFMT), Fernando Corrêa Avenue, 2387, Boa Esperança, Cuiabá, 78060-900, Brazil. rchahn@terra.com.br.ORCID http://orcid.org/0000-0003-2686-8193
Universidade Federal de Mato Grosso · BRHeidelberg University · DEYahoo (Spain) · ES

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance code 001
6 · The paper itself

Abstract

Cryptococcosis is an infection caused by encapsulated basidiomycetous yeasts belonging to the Cryptococcus neoformans/Cryptococcus gattii species complexes. It is acquired through inhalation of infectious propagules, often resulting in meningitis and meningoencephalitis. The ecological niche of these agents is a wide variety of trees species, as well as pigeon, parrot and passerine excreta. The objective of this study was to isolate Cryptococcus yeasts from excreta of commercially traded parrots and passerines. The 237 samples were collected between October 2018 and April 2019 and processed using conventional methodologies. Nineteen colonies with a dark brown phenotype, caused by phenol oxidase activity, were isolated, suggesting the presence of pathogenic Cryptococcus yeasts. All isolates tested positive for urease activity. URA5-RFLP fingerprinting identified 14 isolates (68.4%) as C. neoformans (genotype AFLP1/VNI) and 5 (26.3%) as C. deuterogattii (genotype AFLP6/VGII). Multi-locus sequence typing was applied to investigate the relatedness of the C. deuterogattii isolates with those collected globally, showing that those originating from bird-excreta were genetically indistinguishable from some clinical isolates collected during the past two decades.

Indexed as

CryptococcosisCryptococcus gattiiCryptococcus neoformansAnimalsAntifungal AgentsColumbidaeGenotypeMultilocus Sequence TypingMycological Typing TechniquesParrotsPasseriformesAntifungal AgentsBrazilCryptococcus deuterogattiiCryptococcus gattiiCryptococcus neoformansDomestic birdsExcreta

Identifiers

PMID34762221
PMCPMC8807445
OpenAlexW3211379720

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.