Evidence map›Paper›PMID 34761915›Full record

ReviewACS infectious diseases2021

Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections

Erika L Cyphert, Ningjing Zhang, Greg D Learn, Christopher J Hernandez, Horst A von Recum

Open access · greenAbstract readReview
In one paragraph

Review in ACS infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  3. Total elbow arthroplasty-a historical review.JSES reviews, reports, and techniques · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Erika L CyphertDepartment of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, United States.ORCID 0000-0002-6399-4220
Ningjing ZhangDepartment of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, United States.
Greg D LearnDepartment of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, United States.
Christopher J HernandezSibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, United States.
Horst A von RecumDepartment of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, United States.ORCID 0000-0002-9323-8100
Case Western Reserve University · USHospital for Special Surgery · US

Funding

TRAINING PROGRAM IN MUSCULOSKELETAL RESEARCHT32AR007505 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI TRIOLO, RONALD J · 1986 to 2023
$6.3M
The Microbiome and Bone StrengthR01AG067997 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HERNANDEZ, CHRISTOPHER JOHN · 2021 to 2025
$3.2M
Reducing Adhesions in Hernia Repair Meshes Through a Polysaccharide CoatingR01GM121477 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI VON RECUM, HORST A. · 2017 to 2019
$870k
The microbiome as a risk factor for periprosthetic joint infectionR21AR071534 · NIAMS · HOSPITAL FOR SPECIAL SURGERY · PI BOSTROM, MATHIAS P., HERNANDEZ, CHRISTOPHER JOHN · 2017 to 2018
$431k
NIAMS NIH HHS R21 AR071534NIAMS NIH HHS T32 AR007505NIA NIH HHS R01 AG067997NIGMS NIH HHS R01 GM121477
6 · The paper itself

Abstract

While orthopedic implant-associated infections are rare, revision surgeries resulting from infections incur considerable healthcare costs and represent a substantial research area clinically, in academia, and in industry. In recent years, there have been numerous advances in the development of antimicrobial strategies for the prevention and treatment of orthopedic implant-associated infections which offer promise to improve the limitations of existing delivery systems through local and controlled release of antimicrobial agents. Prior to translation to

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsBiocompatible MaterialsProstheses and ImplantsAnti-Bacterial AgentsAnti-Infective AgentsBiocompatible MaterialsAntibioticDrug deliveryImplantIn vivoPeriprosthetic joint infection

Identifiers

PMID34761915
PMCPMC9704321
OpenAlexW3213472243

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.