Evidence map›Paper›PMID 34761912›Full record

ArticleACS sensors2021

Co-Polarized [1-

Gaurav Sharma, Xiaodong Wen, Nesmine R Maptue, Thomas Hever, Craig R Malloy, A Dean Sherry, Chalermchai Khemtong

Open access · greenAbstract read
In one paragraph

Article in ACS sensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. HyperpolarizedRadiology. Imaging cancer · 2024
    Article
  5. Review
  6. LIGHT-SABRE Hyperpolarizes 1-The journal of physical chemistry. C, Nanomaterials and interfaces · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gaurav SharmaAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.ORCID 0000-0002-1754-7163
Xiaodong WenAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
Nesmine R MaptueAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
Thomas HeverAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
Craig R MalloyAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
A Dean SherryAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
Chalermchai KhemtongAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.ORCID 0000-0003-1976-8098
Southwestern Medical Center · USThe University of Texas at Dallas · USUniversity of Florida · US

Funding

TR&D 3: Imaging Carbohydrate MetabolismP41EB015908 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MALLOY, CRAIG R · 2012 to 2021
$10.9M
Metabolism in the Heart by NMRR37HL034557 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SHERRY, DEAN · 2008 to 2017
$3.9M
Esterase-sensitive hyperpolarized 13C probes for simultaneous imaging of pH and energy metabolismR01EB027698 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI KHEMTONG, CHALERMCHAI · 2020 to 2023
$1.3M
NHLBI NIH HHS R37 HL034557NIBIB NIH HHS P41 EB015908NIBIB NIH HHS R01 EB027698
6 · The paper itself

Abstract

Cellular redox is intricately linked to energy production and normal cell function. Although the redox states of mitochondria and cytosol are connected by shuttle mechanisms, the redox state of mitochondria may differ from redox in the cytosol in response to stress. However, detecting these differences in functioning tissues is difficult. Here, we employed

Indexed as

AcetoacetatesPyruvic AcidAnimalsCytosolLactic AcidMitochondriaOxidation-ReductionRatsAcetoacetatesLactic AcidPyruvic Acidacetoacetatecardiac ischemiahyperpolarized 13C MRpyruvateredox metabolism

Identifiers

PMID34761912
PMCPMC8908480
OpenAlexW3212758596

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.