Evidence map›Paper›PMID 34761697›Full record

ArticleBone & joint research2021

Bi-unicondylar arthroplasty : a biomechanics and clinical outcomes study.

Amy J Garner, Oliver W Dandridge, Andrew A Amis, Justin P Cobb, Richard J van Arkel

Open access · goldAbstract read
In one paragraph

Article in Bone & joint research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Amy J GarnerMSk Lab, Sir Michael Uren Biomedical Engineering Research Hub, Imperial College London, London, UK.ORCID 0000-0001-7839-0641
Oliver W DandridgeBiomechanics Group, Mechanical Engineering Department, Imperial College London, London, UK.ORCID 0000-0002-5829-6209
Andrew A AmisBiomechanics Group, Mechanical Engineering Department, Imperial College London, London, UK.ORCID 0000-0002-4489-1381
Justin P CobbMSk Lab, Sir Michael Uren Biomedical Engineering Research Hub, Imperial College London, London, UK.ORCID 0000-0002-6095-8822
Richard J van ArkelBiomechanics Group, Mechanical Engineering Department, Imperial College London, London, UK.ORCID 0000-0002-1301-1337
Imperial College London · GBCity and Islington College · GBNIHR Imperial Biomedical Research Centre · GBRoyal College of Surgeons of England · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

aimsBi-unicondylar arthroplasty (Bi-UKA) is a bone and anterior cruciate ligament (ACL)-preserving alternative to total knee arthroplasty (TKA) when the patellofemoral joint is preserved. The aim of this study is to investigate the clinical outcomes and biomechanics of Bi-UKA.

methodsBi-UKA subjects (n = 22) were measured on an instrumented treadmill, using standard gait metrics, at top walking speeds. Age-, sex-, and BMI-matched healthy (n = 24) and primary TKA (n = 22) subjects formed control groups. TKA subjects with preoperative patellofemoral or tricompartmental arthritis or ACL dysfunction were excluded. The Oxford Knee Score (OKS) and EuroQol five-dimension questionnaire (EQ-5D) were compared. Bi-UKA, then TKA, were performed on eight fresh frozen cadaveric knees, to investigate knee extensor efficiency under controlled laboratory conditions, using a repeated measures study design.

resultsBi-UKA walked 20% faster than TKA (Bi-UKA mean top walking speed 6.7 km/h (SD 0.9),TKA 5.6 km/h (SD 0.7), p < 0.001), exhibiting nearer-normal vertical ground reaction forces in maximum weight acceptance and mid-stance, with longer step and stride lengths compared to TKA (p < 0.048). Bi-UKA subjects reported higher OKS (p = 0.004) and EQ-5D (p < 0.001). In vitro, Bi-UKA generated the same extensor moment as native knees at low flexion angles, while reduced extensor moment was measured following TKA (p < 0.003). Conversely, at higher flexion angles, the extensor moment of TKA was normal. Over the full range, the extensor mechanism was more efficient following Bi-UKA than TKA (p < 0.028).

conclusionBi-UKA had more normal gait characteristics and improved patient-reported outcomes, compared to matched TKA subjects. This can, in part, be explained by differences in extensor efficiency. Cite this article:

Indexed as

anterior cruciate ligament (ACL)arthroplastiesBi-unicondylar compartmental arthroplastyEQ-5D scoresflexion anglesGait and functional outcomesKnee extensor biomechanicskneesOxford Knee Scorespatellofemoral jointpatient-reported outcomestotal knee arthroplasty (TKA)unicompartmental knee arthroplasty (UKA)

Identifiers

PMID34761697
PMCPMC8636181
OpenAlexW3212810151

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.