ArticleThe New phytologist2022
MoErv29 promotes apoplastic effector secretion contributing to virulence of the rice blast fungus Magnaporthe oryzae.
Article in The New phytologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Fungal Carbonic Anhydrases: A Systematic Review from Molecular Profiling to Pathogenic Regulation inJournal of fungi (Basel, Switzerland) · 2026Review
- Genome-wide prediction of secretory proteins in Ceratocystis paradoxa and expression analysis of effectors during early infection.BMC microbiology · 2026Article
- A fungal nuclease effector subverts the chloroplast genome and triggers cell death to promote infection.Nature plants · 2026Article
- The Guanine Exchange FactorJournal of fungi (Basel, Switzerland) · 2025Article
- FgNdk1 Promotes Effector Secretion to Scavenge ROS During Fusarium graminearum Infection.Molecular plant pathology · 2025Article
- MoSec13 combined with MoGcn5b modulates MoAtg8 acetylation and regulates autophagy inAutophagy · 2025Article
- Golgin Protein MoCoy1 Mediates Retrograde Trafficking From the Golgi to the ER, Regulating Fungal Development and Pathogenicity in Magnaporthe oryzae.Molecular plant pathology · 2025Article
- The transcription factor CfHac1 regulates the degradation of ubiquitin-mediated ER-associated misfolded proteins and pathogenicity in Colletotrichum fructicola.Stress biology · 2025Article
- Pyricularia oryzae: Lab star and field scourge.Molecular plant pathology · 2024Review
- The schizotrophic lifestyle of Sclerotinia sclerotiorum.Molecular plant pathology · 2024Review
- Infection-specific transcriptional patterns of the maize pathogen Cochliobolus heterostrophus unravel genes involved in asexual development and virulence.Molecular plant pathology · 2024Article
- Autophagy and cell wall integrity pathways coordinately regulate the development and pathogenicity through MoAtg4 phosphorylation in Magnaporthe oryzae.PLoS pathogens · 2024Article
- Recent Advances in Effector Research ofBiomolecules · 2023Review
- An Ustilaginoidea virens glycoside hydrolase 42 protein is an essential virulence factor and elicits plant immunity as a PAMP.Molecular plant pathology · 2023Article
- Methionine biosynthesis enzyme MoMet2 is required for rice blast fungus pathogenicity by promoting virulence gene expression via reducing 5mC modification.PLoS genetics · 2023Article
- Interplay of transport vesicles during plant-fungal pathogen interaction.Stress biology · 2023Review
- MoErv14 mediates the intracellular transport of cell membrane receptors to govern the appressorial formation and pathogenicity of Magnaporthe oryzae.PLoS pathogens · 2023Article
- Two nucleotide sugar transporters are important for cell wall integrity and full virulence of Magnaporthe oryzae.Molecular plant pathology · 2023Article
- Pectate Lyase Genes Abundantly Expressed During the Infection Regulate Morphological Development ofmSphere · 2023Article
- MoMaf1 Mediates Vegetative Growth, Conidiogenesis, and Pathogenicity in the Rice Blast FungusJournal of fungi (Basel, Switzerland) · 2023Article
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10 authors.
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Abstract
During plant-pathogenic fungi and host plants interactions, numerous pathogen-derived proteins are secreted resulting in the activation of the unfolded protein response (UPR) pathway. For efficient trafficking of secretory proteins, including those important in disease progression, the cytoplasmic coat protein complex II (COPII) exhibits a multifunctional role whose elucidation remains limited. Here, we discovered that the COPII cargo receptor MoErv29 functions as a target of MoHac1, a previously identified transcription factor of the UPR pathway. In Magnaporthe oryzae, deletion of MoERV29 severely affected the vegetative growth, conidiation and biotrophic invasion of the fungus in susceptible rice hosts. We demonstrated that MoErv29 is required for the delivery of secreted proteins through recognition and binding of the amino-terminal tripeptide motifs following the signal peptide. By using bioinformatics analysis, we predicted a cargo spectrum of MoErv29 and found that MoErv29 is required for the secretion of many proteins, including extracellular laccases and apoplastic effectors. This secretion is mediated through the conventional endoplasmic reticulum-Golgi secretion pathway and is important for conferring host recognition and disease resistance. Taken together, our results revealed how MoErv29 operates on effector secretion, and our findings provided a critical link between COPII vesicle trafficking and the UPR pathway.
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