Evidence map›Paper›PMID 34761145›Full record

ArticleJBMR plus2021

Abnormal Bone Tissue Organization and Osteocyte Lacunocanalicular Network in Early-Onset Osteoporosis Due to

Riikka E Mäkitie, Stéphane Blouin, Ville-Valtteri Välimäki, Sandra Pihlström, Kirsi Määttä, Minna Pekkinen, Nadja Fratzl-Zelman, Outi Mäkitie, Markus A Hartmann

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. PathogenicFrontiers in endocrinology · 2026
    Article
  2. Article
  3. Article
  4. Approaching virtual osteoid volume estimation and in-depth tissue characterization in patients with tumor-induced osteomalacia.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  5. Bone fragility and osteoporosis in children and young adults.Journal of endocrinological investigation · 2024
    Review
  6. Article
  7. Frontiers in endocrinology · 2023
    Review
  8. Article
  9. Early-Onset Osteoporosis: Rare Monogenic Forms Elucidate the Complexity of Disease Pathogenesis Beyond Type I Collagen.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Riikka E MäkitieFolkhälsan Institute of Genetics Helsinki Finland.ORCID https://orcid.org/0000-0002-2907-3348
Stéphane BlouinLudwig Boltzmann Institute of Osteology at Hanusch Hospital of OEGK and AUVA Trauma Centre Meidling, 1st Medical Department Hanusch Hospital Vienna Austria.
Ville-Valtteri VälimäkiPohjola Hospital Helsinki Finland.
Sandra PihlströmFolkhälsan Institute of Genetics Helsinki Finland.
Kirsi MäättäFolkhälsan Institute of Genetics Helsinki Finland.
Minna PekkinenFolkhälsan Institute of Genetics Helsinki Finland.
Nadja Fratzl-ZelmanLudwig Boltzmann Institute of Osteology at Hanusch Hospital of OEGK and AUVA Trauma Centre Meidling, 1st Medical Department Hanusch Hospital Vienna Austria.ORCID https://orcid.org/0000-0003-1164-1877
Outi MäkitieFolkhälsan Institute of Genetics Helsinki Finland.ORCID https://orcid.org/0000-0002-4547-001X
Markus A HartmannLudwig Boltzmann Institute of Osteology at Hanusch Hospital of OEGK and AUVA Trauma Centre Meidling, 1st Medical Department Hanusch Hospital Vienna Austria.ORCID https://orcid.org/0000-0001-6046-0365
University of Helsinki · FIStatistics Austria · ATNorthern Ostrobothnia Hospital District · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathological variants in

Indexed as

BONE HISTOMORPHOMETRYCONFOCAL LASER SCANNING MICROSCOPYEARLY‐ONSET OSTEOPOROSISQUANTITATIVE BACKSCATTERED ELECTRON IMAGINGSPHINGOMYELIN METABOLISMSPHINGOMYELIN SYNTHASE 2

Identifiers

PMID34761145
PMCPMC8567487
OpenAlexW3187393226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.