Evidence map›Paper›PMID 34761004›Full record

ArticleBioMed research international2021

Cytotoxic and Antifungal Amides Derived from Ferulic Acid: Molecular Docking and Mechanism of Action.

Mayara Castro de Morais, Yunierkis Perez-Castillo, Valdenizia Rodrigues Silva, Luciano de Souza Santos, Milena Botelho Pereira Soares, Daniel Pereira Bezerra, Ricardo Dias de Castro, Damião Pergentino de Sousa

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Antifungal activity against Candida albicans of methyl 3,5-dinitrobenzoate loaded nanoemulsion.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Mayara Castro de MoraisLaboratory of Pharmaceutical Chemistry, Department of Pharmaceutical Sciences, Federal University of Paraíba, 58051-900 João Pessoa, PB, Brazil.ORCID https://orcid.org/0000-0001-5967-9554
Yunierkis Perez-CastilloEscuela de Ciencias Físicas y Matemáticas, Universidad de Las Américas, Quito, Ecuador.ORCID https://orcid.org/0000-0002-3710-0035
Valdenizia Rodrigues SilvaInstituto Gonçalo Moniz, Fundação Oswaldo Cruz (IGM-FIOCRUZ/BA), Salvador, 40296-710 Bahia, Brazil.ORCID https://orcid.org/0000-0001-8717-0501
Luciano de Souza SantosInstituto Gonçalo Moniz, Fundação Oswaldo Cruz (IGM-FIOCRUZ/BA), Salvador, 40296-710 Bahia, Brazil.ORCID https://orcid.org/0000-0002-1381-1342
Milena Botelho Pereira SoaresInstituto Gonçalo Moniz, Fundação Oswaldo Cruz (IGM-FIOCRUZ/BA), Salvador, 40296-710 Bahia, Brazil.ORCID https://orcid.org/0000-0001-7549-2992
Daniel Pereira BezerraInstituto Gonçalo Moniz, Fundação Oswaldo Cruz (IGM-FIOCRUZ/BA), Salvador, 40296-710 Bahia, Brazil.ORCID https://orcid.org/0000-0002-6774-2063
Ricardo Dias de CastroLaboratory of Experimental Pharmacology and Cell Culture, Department of Clinical and Social Dentistry, Federal University of Paraíba, 58051-900, Joao Pessoa, PB, Brazil.ORCID https://orcid.org/0000-0001-7986-7376
Damião Pergentino de SousaLaboratory of Pharmaceutical Chemistry, Department of Pharmaceutical Sciences, Federal University of Paraíba, 58051-900 João Pessoa, PB, Brazil.ORCID https://orcid.org/0000-0002-7180-4896
Fundação Oswaldo Cruz · BRUniversidade Federal da Paraíba · BRUniversidad de Las Américas · EC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amides derived from ferulic acid have a wide spectrum of pharmacological activities, including antitumor and antifungal activity. In the present study, a series of ten amides were obtained by coupling reactions using the reagents (benzotriazol-1-yloxy) tripyrrolidinophosphonium hexafluorophosphate (PyBOP) and

Indexed as

AmidesAntifungal AgentsCandidaCoumaric AcidsDicyclohexylcarbodiimideInhibitory Concentration 50Microbial Sensitivity TestsMolecular Docking SimulationOils, VolatileOrganophosphorus CompoundsTriazolesAmidesAntifungal Agentsbenzotriazol-1-yloxtri (pyrrolidinol)phosphonium hexafluorophosphateCoumaric AcidsDicyclohexylcarbodiimideferulic acidOils, VolatileOrganophosphorus CompoundsTriazoles

Identifiers

PMID34761004
PMCPMC8575619
OpenAlexW3210755570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.