Evidence map›Paper›PMID 34761000›Full record

ArticleERJ open research2021

Normal limits for oscillometric bronchodilator responses and relationships with clinical factors.

Kanika Jetmalani, Nathan J Brown, Chantale Boustany, Brett G Toelle, Guy B Marks, Michael J Abramson, David P Johns, Alan L James, Michael Hunter, Arthur W Musk and 5 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Improving asthma outcomes: Clinicians' perspectives on peripheral airways.The journal of allergy and clinical immunology. Global · 2024
    Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Reference equations for oscillometry and their differences among populations: a systematic scoping review.European respiratory review : an official journal of the European Respiratory Society · 2022
    Article
  11. Clinical significance and applications of oscillometry.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Kanika JetmalaniThe Woolcock Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Nathan J BrownThe Woolcock Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Chantale BoustanyThe Woolcock Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Brett G ToelleThe Woolcock Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.ORCID https://orcid.org/0000-0002-7375-0019
Guy B MarksThe Woolcock Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.ORCID https://orcid.org/0000-0002-8976-8053
Michael J AbramsonSchool of Population Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0002-9954-0538
David P JohnsCollege of Health and Medicine, University of Tasmania, Hobart, TAS, Australia.
Alan L JamesBusselton Population Medical Research Institute, Busselton, WA, Australia.
Michael HunterBusselton Population Medical Research Institute, Busselton, WA, Australia.
Arthur W MuskBusselton Population Medical Research Institute, Busselton, WA, Australia.
Norbert BerendThe Woolcock Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Claude S FarahThe Woolcock Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.ORCID https://orcid.org/0000-0003-2489-227X
David G ChapmanThe Woolcock Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.ORCID https://orcid.org/0000-0002-8211-1817
Cindy ThamrinThe Woolcock Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.ORCID https://orcid.org/0000-0003-3284-3558
Gregory G KingThe Woolcock Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
The University of Sydney · AUThe University of Western Australia · AUMonash University · AUUniversity of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe aimed to determine normal thresholds for positive bronchodilator responses for oscillometry in an Australian general population sample aged ≥40 years, to guide clinical interpretation. We also examined relationships between bronchodilator responses and respiratory symptoms, asthma diagnosis, smoking and baseline lung function.

methodsSubjects recruited from Sydney, Melbourne and Busselton, Australia, underwent measurements of spirometry, resistance (

resultsOf 1318 participants, 1145 (570 female) were analysed. The lower threshold for Δ DISCUSSION: This study describes normative thresholds for bronchodilator responses in oscillometry parameters, including intra-breath parameters, as determined by absolute, relative and Z-score changes. Positive bronchodilator response by oscillometry correlated with clinical factors and baseline function, which may inform the clinical interpretation of oscillometry.

Identifiers

PMID34761000
PMCPMC8573235
OpenAlexW3200244479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.