Evidence map›Paper›PMID 34760696›Full record

ReviewFrontiers in oncology2021

Advancement of Scaffold-Based 3D Cellular Models in Cancer Tissue Engineering: An Update.

Kavitha Unnikrishnan, Lynda Velutheril Thomas, Ram Mohan Ram Kumar

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 86 citations in OpenAlex.

  1. Biomimetic Scaffold-Based 3D Models for Decoding Cancer Biology and Advancing Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Review
  3. Review
  4. Dynamic Hydrogels in Breast Tumor Models.Gels (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. RSC advances · 2024
    Article
  18. Advanced Hydrogels in Breast Cancer Therapy.Gels (Basel, Switzerland) · 2024
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kavitha UnnikrishnanDepartment of Cancer Research, Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, India.
Lynda Velutheril ThomasDivision of Tissue Engineering & Regenerative Technology, Sree Chitra Thirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, India.
Ram Mohan Ram KumarDepartment of Cancer Research, Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, India.
Rajiv Gandhi Centre for Biotechnology · INSree Chitra Thirunal Institute for Medical Sciences and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lack of traditional cancer treatments has resulted in an increased need for new clinical techniques. Standard two-dimensional (2D) models used to validate drug efficacy and screening have a low

Indexed as

3D scaffoldcancercellular interactionextracellular matrix (ECM)tissue engineering

Identifiers

PMID34760696
PMCPMC8573168
OpenAlexW3209046012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.