Evidence map›Paper›PMID 34760673›Full record

ArticleIndian journal of endocrinology and metabolism

Thyroid Dysfunction in COVID-19.

Aashima Dabas, Harpreet Singh, Binita Goswami, Kunal Kumar, Abhishek Dubey, Urmila Jhamb, Sangeeta Yadav, Sandeep Garg

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Thyroiditis and COVID-19: focus on pediatric age. A narrative review.Journal of endocrinological investigation · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Thyroid Dysfunction among the Patients with Critical COVID-19.Infectious diseases & clinical microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aashima DabasDepartment of Pediatrics, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Harpreet SinghDepartment of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Binita GoswamiDepartment of Biochemistry, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Kunal KumarDepartment of Pediatrics, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Abhishek DubeyDepartment of Biochemistry, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Urmila JhambDepartment of Pediatrics, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Sangeeta YadavDepartment of Pediatrics, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Sandeep GargDepartment of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Maulana Azad Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to evaluate thyroid dysfunction in COVID-19 and study its association with disease severity in COVID-19.

methodsPatients with confirmed COVID-19 infection who were admitted to dedicated COVID hospital were recruited over 3 months period. Those with pre-existing thyroid disease were excluded. The thyroid function tests were performed and correlated with interleukin-6 levels.

resultsA total of 164 patients (14 children) with mean(SD) age 53.85 (19.54) years were recruited. The proportion of patients with mild, moderate and severe disease were 22 (13.4%), 78 (47.6%) and 64 (39.0%), respectively, among which 12 (54.5%), 56 (71.8%) and 43 (67.2%) patients had thyroid dysfunction, respectively;

conclusionSick euthyroid was seen in the majority of patients hospitalized with COVID. Low fT3 was associated with death and increased inflammation, suggesting poor prognosis.

Indexed as

HypothyroidismIL-6inflammatory markersick euthyroidthyroiditis

Identifiers

PMID34760673
PMCPMC8547402
OpenAlexW3208326050

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.