Evidence map›Paper›PMID 34760657›Full record

ArticleInternational journal of critical illness and injury science

Validation of the vasoactive-inotropic score in predicting pediatric septic shock mortality: A retrospective cohort study.

Antonius Hocky Pudjiadi, Dwi Lestari Pramesti, Sudung O Pardede, Mulyadi M Djer, Rinawati Rohsiswatmo, Nastiti Kaswandani

Abstract read
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Article in International journal of critical illness and injury science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

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8citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  8. Vasoactive-inotropic score and pediatric septic shock mortality: Correspondence.International journal of critical illness and injury science
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Antonius Hocky PudjiadiDepartment of Child-Health, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia.
Dwi Lestari PramestiDepartment of Child-Health, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia.
Sudung O PardedeDepartment of Child-Health, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia.
Mulyadi M DjerDepartment of Child-Health, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia.
Rinawati RohsiswatmoDepartment of Child-Health, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia.
Nastiti KaswandaniDepartment of Child-Health, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMortality in pediatric septic shock remains very high. Vasoactive-inotropic score (VIS) is widely used to predict prognosis in patients with heart disease. It is a simple method that was initially used as a predictor of morbidity and mortality in postoperative patients with congenital heart diseases. Previous reports showed that high VIS score was associated with high mortality in pediatric sepsis. However, its discriminative value remains unclear. We aim to explore the discriminative value of VIS in predicting mortality in pediatric septic shock patients.

methodsWe conducted a retrospective cohort study on medical records of septic shock patients who received care in the pediatric intensive care unit (PICU). We screened medical records of pediatric patients which were diagnosed with septic shock and admitted to the PICU and received vasoactive/inotropic score for more than 8 h. Other supporting examination results were recorded, such as organ function evaluation for calculation of Pediatric Logistic Organ Dysfunction-2 (PELOD-2) score. The outcome of patients was recorded. The receiver operating curve was constructed to calculate the area under the curve (AUC), sensitivity, and specificity of each cutoff point.

resultsWe obtained the optimum cutoff point of VIS > 11 with 78.87% sensitivity and 72.22% specificity. AUC positive was 0.779 (

conclusionVIS > 11 has a good ability to predict mortality in children with septic shock.

Indexed as

Mortalitypediatricssepsisvasoactive-inotropic score

Identifiers

PMID34760657
PMCPMC8547676

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.