Evidence map›Paper›PMID 34760366›Full record

ArticlePeerJ2021

Obesity phenotypes and their relationships with atrial fibrillation.

Szu-Ying Tsai, Hsin-Hao Chen, Hsin-Yin Hsu, Ming-Chieh Tsai, Le-Yin Hsu, Lee-Ching Hwang, Kuo-Liong Chien, Chien-Ju Lin, Tzu-Lin Yeh

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Szu-Ying TsaiDepartment of Family Medicine, Taipei City Hospital, Zhongxing Branch, Taipei City, Taiwan.ORCID 0000-0002-5349-5022
Hsin-Hao ChenDepartment of Family Medicine, Hsinchu MacKay Memorial Hospital, Hsinchu City, Taiwan.ORCID 0000-0001-5785-8882
Hsin-Yin HsuDepartment of Family Medicine, Taipei MacKay Memorial Hospital, Taipei City, Taiwan.
Ming-Chieh TsaiDivision of Endocrinology and Metabolism, Department of Internal Medicine, Taipei MacKay Memorial Hospital, Taipei City, Taiwan.
Le-Yin HsuInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei City, Taiwan.
Lee-Ching HwangDepartment of Family Medicine, Taipei MacKay Memorial Hospital, Taipei City, Taiwan.
Kuo-Liong ChienInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei City, Taiwan.ORCID 0000-0003-4979-8351
Chien-Ju LinDepartment of Family Medicine, Hsinchu MacKay Memorial Hospital, Hsinchu City, Taiwan.ORCID 0000-0002-6825-677X
Tzu-Lin YehDepartment of Family Medicine, Hsinchu MacKay Memorial Hospital, Hsinchu City, Taiwan.ORCID 0000-0003-1894-0394
Mackay Memorial Hospital · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study assessed the associations of metabolic obesity phenotypes with the risk of atrial fibrillation (Afib).

methodsThis prospective cohort study categorized Taiwanese adults according to their body mass index (BMI) and metabolic health status at baseline. We assigned the participants to the underweight (BMI < 18.5 kg/m

resultsIn total, 5,742 adults were included. During a median follow-up of 13.7 years, 148 patients developed Afib. Compared to the metabolically healthy normal weight group, the risk of Afib was significantly higher than those in the metabolically unhealthy overweight/obesity (hazard ratio = 2.20, 95% confidence interval [1.12-4.33]) and metabolically unhealthy normal weight groups (HR = 2.64, 95% CI [1.34-5.17]). Additionally, the point estimate suggested a 1.97-fold greater risk among the metabolically healthy overweight/obesity group, although this difference was not significant given the wide confidence interval (HR = 1.97, 95% CI [0.80-4.86]).

conclusionOur results demonstrated the relationships of metabolic health and weight regarding the risk of Afib in Taiwanese adults. The Afib risk among metabolic and obesity phenotypes is associated with a metabolically unhealthy status. A trend toward a higher Afib risk with obesity among metabolically healthy subjects was observed. However, the result was not robust and it still suggested further study.

Indexed as

Atrial fibrillationMetabolically healthy obesityMetabolically unhealthyMetabolic obesity phenotypesMetabolic syndrome

Identifiers

PMID34760366
PMCPMC8557684
OpenAlexW3209524547

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.