Evidence map›Paper›PMID 34760212›Full record

ArticleChemical science2021

Surface-controlled spatially heterogeneous physical properties of a supramolecular gel with homogeneous chemical composition.

Bin Yang, Marina Lledos, Riaz Akhtar, Giuseppe Ciccone, Long Jiang, Emanuele Russo, Sunil Rajput, Chunyu Jin, Maria Galini Faidra Angelereou, Thomas Arnold and 5 more

Abstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Reversibly Tuning the Viscosity of Peptide-Based Solutions Using Visible Light.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  2. Personal Perspective on Understanding Low Molecular Weight Gels.Journal of the American Chemical Society · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Bin YangDepartment of Pharmacy, University of Nottingham Nottingham NG2 7RD UK mischa.zelzer@nottingham.ac.uk.
Marina LledosDepartment of Pharmacy, University of Nottingham Nottingham NG2 7RD UK mischa.zelzer@nottingham.ac.uk.
Riaz AkhtarDepartment of Mechanical, Materials and Aerospace Engineering, School of Engineering, University of Liverpool Liverpool L69 3GH UK.
Giuseppe CicconeCentre for the Cellular Microenvironment, University of Glasgow Glasgow G12 8LT UK.ORCID https://orcid.org/0000-0002-7677-6257
Long JiangDepartment of Pharmacy, University of Nottingham Nottingham NG2 7RD UK mischa.zelzer@nottingham.ac.uk.ORCID https://orcid.org/0000-0002-0215-0913
Emanuele RussoDepartment of Pharmacy, University of Nottingham Nottingham NG2 7RD UK mischa.zelzer@nottingham.ac.uk.
Sunil RajputDepartment of Pharmacy, University of Nottingham Nottingham NG2 7RD UK mischa.zelzer@nottingham.ac.uk.
Chunyu JinDepartment of Chemical Engineering and Biotechnology, University of Cambridge Cambridge CB3 0AS UK.
Maria Galini Faidra AngelereouDepartment of Pharmacy, University of Nottingham Nottingham NG2 7RD UK mischa.zelzer@nottingham.ac.uk.
Thomas ArnoldDiamond Light Source Ltd Harwell Science and Innovation Campus Didcot Oxfordshire OX11 0DE UK.ORCID https://orcid.org/0000-0001-8295-3822
Jonathan RawleDiamond Light Source Ltd Harwell Science and Innovation Campus Didcot Oxfordshire OX11 0DE UK.
Massimo VassalliCentre for the Cellular Microenvironment, University of Glasgow Glasgow G12 8LT UK.ORCID https://orcid.org/0000-0002-3063-4376
Maria MarlowDepartment of Pharmacy, University of Nottingham Nottingham NG2 7RD UK mischa.zelzer@nottingham.ac.uk.
Dave J AdamsSchool of Chemistry, University of Glasgow University Avenue Glasgow G12 8QQ UK.ORCID https://orcid.org/0000-0002-3176-1350
Mischa ZelzerDepartment of Pharmacy, University of Nottingham Nottingham NG2 7RD UK mischa.zelzer@nottingham.ac.uk.ORCID https://orcid.org/0000-0002-6086-2206

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Controlling supramolecular self-assembly across multiple length scales to prepare gels with localised properties is challenging. Most strategies concentrate on fabricating gels with heterogeneous components, where localised properties are generated by the stimuli-responsive component. Here, as an alternative approach, we use a spiropyran-modified surface that can be patterned with light. We show that light-induced differences in surface chemistry can direct the bulk assembly of a low molecular weight gelator, 2-NapAV, meaning that mechanical gel properties can be controlled by the surface on which the gel is grown. Using grazing incidence X-ray diffraction and grazing incidence small angle X-ray scattering, we demonstrate that the origin of the different gel properties relates to differences in the architectures of the gels. This provides a new method to prepare a single domain (

Identifiers

PMID34760212
PMCPMC8565383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.