Evidence map›Paper›PMID 34760197›Full record

ArticleChemical science2021

An enzyme-mediated bioorthogonal labeling method for genome-wide mapping of 5-hydroxymethyluracil.

Cheng-Jie Ma, Lin Li, Wen-Xuan Shao, Jiang-Hui Ding, Xiao-Li Cai, Zhao-Rong Lun, Bi-Feng Yuan, Yu-Qi Feng

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Genome-wide mapping ofChemical science · 2022
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Cheng-Jie MaSauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 China bfyuan@whu.edu.cn.
Lin LiSchool of Pharmacy, Shanghai Jiao Tong University Shanghai 200240 P. R. China.ORCID https://orcid.org/0000-0002-5891-9816
Wen-Xuan ShaoSauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 China bfyuan@whu.edu.cn.
Jiang-Hui DingSauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 China bfyuan@whu.edu.cn.
Xiao-Li CaiCenter for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University Guangzhou 510275 P. R. China.
Zhao-Rong LunCenter for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University Guangzhou 510275 P. R. China.
Bi-Feng YuanSauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 China bfyuan@whu.edu.cn.ORCID https://orcid.org/0000-0001-5223-4659
Yu-Qi FengSauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 China bfyuan@whu.edu.cn.ORCID https://orcid.org/0000-0003-1107-5385
Wuhan University · CNSun Yat-sen University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA 5-hydroxymethyluracil (5hmU) is a thymine modification existing in the genomes of various organisms. The post-replicative formation of 5hmU occurs

Identifiers

PMID34760197
PMCPMC8565368
OpenAlexW3203967801

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.