Evidence map›Paper›PMID 34759837›Full record

ArticleFrontiers in physiology2021

Comparative Study of Human and Murine Aortic Biomechanics and Hemodynamics in Vascular Aging.

Sara E Hopper, Federica Cuomo, Jacopo Ferruzzi, Nicholas S Burris, Sara Roccabianca, Jay D Humphrey, C Alberto Figueroa

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Cerebral arteries in mice with sickle cell disease are exposed to larger areas of low wall shear stress.American journal of physiology. Heart and circulatory physiology · 2026
    Article
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  6. Review
  7. Living myocardial slices as a model for testing cardiac pro-reparative gene therapies.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  8. Article
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  10. Article
  11. Review
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  18. The extracellular matrix mechanics in the vasculature.Nature cardiovascular research · 2023
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Sara E HopperDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States.
Federica CuomoDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States.
Jacopo FerruzziDepartment of Bioengineering, The University of Texas at Dallas, Richardson, TX, United States.
Nicholas S BurrisDepartment of Radiology, University of Michigan, Ann Arbor, MI, United States.
Sara RoccabiancaDepartment of Mechanical Engineering, Michigan State University, East Lansing, MI, United States.
Jay D HumphreyDepartment of Biomedical Engineering, Yale University, New Haven, CT, United States.
C Alberto FigueroaDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · USMichigan State University · USThe University of Texas at Dallas · USYale University · US

Funding

Mechanisms Underlying The Progression of Large Artery Stiffness in HypertensionR01HL105297 · NHLBI · YALE UNIVERSITY · PI FIGUEROA, CARLOS ALBERTO, HUMPHREY, JAY D. · 2010 to 2019
$3.0M
Image-based Multi-scale Modeling Framework of the Cardiopulmonary System: Longitudinal Calibration and Assessment of Therapies in Pediatric Pulmonary HypertensionU01HL135842 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BAEK, SEUNGIK, DORFMAN, ADAM LEE · 2017 to 2020
$2.3M
NHLBI NIH HHS R01 HL105297NHLBI NIH HHS U01 HL135842
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

aortic morphologyarterial stiffnessfluid-solid-interactionhypertensionpulse wave velocity (PWV)

Identifiers

PMID34759837
PMCPMC8573132
OpenAlexW3209493239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.