Evidence map›Paper›PMID 34759834›Full record

ArticleFrontiers in physiology2021

Cellular Size, Gap Junctions, and Sodium Channel Properties Govern Developmental Changes in Cardiac Conduction.

Madison B Nowak, Rengasayee Veeraraghavan, Steven Poelzing, Seth H Weinberg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Cardiac Impulse Propagation: An Integrated View.JACC. Basic to translational science · 2026
    Review
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  4. Electroanatomical adaptations in the guinea pig heart from neonatal to adulthood.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
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  12. Review
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  16. Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Madison B NowakDepartment of Biomedical Engineering, The Ohio State University, Columbus, OH, United States.
Rengasayee VeeraraghavanDepartment of Biomedical Engineering, The Ohio State University, Columbus, OH, United States.
Steven PoelzingDepartment of Biomedical Engineering and Mechanics, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States.
Seth H WeinbergDepartment of Biomedical Engineering, The Ohio State University, Columbus, OH, United States.
The Ohio State University · USVirginia Tech · US

Funding

Targeting Vascular Leak and Intercalated Disk Nanodomains to Prevent Atrial FibrillationR01HL148736 · NHLBI · OHIO STATE UNIVERSITY · PI VEERARAGHAVAN, RENGASAYEE · 2020 to 2024
$2.2M
NHLBI NIH HHS R01 HL148736
6 · The paper itself

Abstract

Electrical conduction in cardiac ventricular tissue is regulated via sodium (Na

Indexed as

cardiac conductioncardiac electrophysiologycomputational modelsdevelopmentintercalated disc

Identifiers

PMID34759834
PMCPMC8573326
OpenAlexW3210448721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.