Evidence map›Paper›PMID 34759811›Full record

ArticleFrontiers in aging neuroscience2021

Arterial Stiffening Moderates the Relationship Between Type-2 Diabetes Mellitus and White Matter Hyperintensity Burden in Older Adults With Mild Cognitive Impairment.

Madeleine L Werhane, Kelsey R Thomas, Katherine J Bangen, Alexandra J Weigand, Emily C Edmonds, Daniel A Nation, Erin E Sundermann, Mark W Bondi, Lisa Delano-Wood

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Insights into Cognitive Brain Health in Chronic Kidney Disease.Gerontology & geriatrics : research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Madeleine L WerhaneDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.
Kelsey R ThomasVA San Diego Healthcare System, San Diego, CA, United States.
Katherine J BangenVA San Diego Healthcare System, San Diego, CA, United States.
Alexandra J WeigandVA San Diego Healthcare System, San Diego, CA, United States.
Emily C EdmondsVA San Diego Healthcare System, San Diego, CA, United States.
Daniel A NationDepartment of Psychological Sciences, University of California, Irvine, Irvine, CA, United States.
Erin E SundermannDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, United States.
Mark W BondiVA San Diego Healthcare System, San Diego, CA, United States.
Lisa Delano-WoodVA San Diego Healthcare System, San Diego, CA, United States.
VA San Diego Healthcare System · USUniversity of California, San Diego · USUniversity of California, Irvine · USUniversity of Washington · US

Funding

UC Irvine Alzheimer's Disease Research Center Induced Pluripotent Stem Cell CoreP50AG016573 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI LAFERLA, FRANK M · 2000 to 2019
$37.0M
UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Steven Dyal Edland · 2019 to 2026
$34.9M
Vascular Contributions to Dementia and Genetic Risk Factors for Alzheimer's DiseaseP01AG052350 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Daniel A Nation, ARTHUR W TOGA · 2016 to 2026
$28.4M
Endothelial progenitor cells and neurovascular injury in the aging brainR01AG064228 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Daniel A Nation · 2019 to 2026
$4.5M
Cerebrovascular resistance in cognitive aging and Alzheimer's disease riskR01AG060049 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI NATION, DANIEL A · 2020 to 2023
$2.4M
CSRD VA I01 CX001842CSRD VA IK2 CX001865NIA NIH HHS P01 AG052350NIA NIH HHS P30 AG062429NIA NIH HHS P50 AG016573NIA NIH HHS R01 AG060049NIA NIH HHS R01 AG064228
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

arterial stiffnessblood pressurediabetesmild cognitive impairmentwhite matter hyperintensity volume

Identifiers

PMID34759811
PMCPMC8574966
OpenAlexW3208398182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.