Evidence map›Paper›PMID 34759665›Full record

ArticleMiddle East African journal of ophthalmology

Burden and Presentation of Age-Related Macular Degeneration among Nigerians.

Ogugua N Okonkwo, Affiong Ibanga, Olukorede Adenuga, Dennis Nkanga, Wilson Ovienra, Chineze T Agweye, Toyin Akanbi, Idris Oyekunle, Martha-Mary Udoh

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Middle East African journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Multimodal imaging of experimental choroidal neovascularization.International journal of ophthalmology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ogugua N OkonkwoDepartment of Ophthalmology, Eye Foundation Hospital, Lagos, Nigeria.
Affiong IbangaDepartment of Ophthalmology, University of Calabar Teaching Hospital, Calabar, Nigeria.
Olukorede AdenugaDepartment of Ophthalmology, Jos University Teaching Hospital, Jos, Nigeria.
Dennis NkangaDepartment of Ophthalmology, University of Calabar Teaching Hospital, Calabar, Nigeria.
Wilson OvienraDepartment of Ophthalmology, Irrua Specialist Hospital, Edo, Nigeria.
Chineze T AgweyeDepartment of Ophthalmology, University of Calabar Teaching Hospital, Calabar, Nigeria.
Toyin AkanbiDepartment of Ophthalmology, Eye Foundation Hospital, Lagos, Nigeria.
Idris OyekunleDepartment of Ophthalmology, Eye Foundation Hospital, Lagos, Nigeria.
Martha-Mary UdohDepartment of Ophthalmology, University of Calabar Teaching Hospital, Calabar, Nigeria.
University of Calabar · NGLagos University Teaching Hospital · NGIrrua Specialist Teaching Hospital · NGJos University Teaching Hospital · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAge-related macular degeneration (AMD) is a leading cause of visual impairment worldwide, and its prevalence may also be on the increase in Nigeria. The purpose of this study is to ascertain the burden and pattern of presentation of AMD in a developing country.

methodsWe conducted a multicenter, prospective study from January to December 2018. Biodata and history of systemic disease were obtained from consecutive patients presenting at four collaborating retina clinics and diagnosed with a retina disease after dilated fundus examination and ocular investigations such as fundus photography, fluorescein angiography, and optical coherence tomography. All eyes diagnosed to have wet and dry AMD were used for the study analysis.

resultsOut of 8614 patients, 156 eyes of 78 patients were diagnosed with AMD. The hospital-based prevalence for AMD was 0.91%. The mean age at presentation was 67.9 ± 9.2 years, ranging from 44 to 95 years. A majority (75.6%) of patients were between 60 and 79 years, 53.8% were females. Thirty-two eyes (20.5%) had wet AMD, while 124 eyes (79.5%) had dry AMD. Sixty-one eyes (39.1%) had moderate visual impairment (<6/18-6/60); 58 eyes (37.2%) had normal vision (6/18 and better); while 27 eyes (17.3%) were blind, and ten eyes (6.4%) had severe visual impairment.

conclusionAMD contributes to the burden of visual impairment and blindness in the elderly Nigerian. In Nigeria, AMD occurs more in females and most common between the ages of 60 and 79. Dry AMD is four times more common than wet AMD. About 24% of eyes have severe visual impairment or blindness, while about a third each have a moderate visual impairment and normal vision. Increasing awareness of AMD among the at-risk population will be beneficial in achieving early diagnosis and treatment.

Indexed as

Wet Macular DegenerationAgedFemaleFluorescein AngiographyHumansMiddle AgedNigeriaProspective StudiesTomography, Optical CoherenceAgeingage-related macular degenerationblindnessNigeriavisual impairment

Identifiers

PMID34759665
PMCPMC8547669
OpenAlexW3201940848

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.