Evidence map›Paper›PMID 34759561›Full record

ArticleJournal of anaesthesiology, clinical pharmacology

Implementation of a risk-stratified approach to prevent postoperative nausea and vomiting in an institution with high baseline rates of prophylaxis.

Kadhiresan R Murugappan, Mario Moric, Xuanji Wang, Jessica Kruse, Ariel Mueller, Myles D Boone, Cristina Barboi

Abstract read
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In one paragraph

Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Anesthesia for uterine transplantation.Anesthesia and pain medicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kadhiresan R MurugappanDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, One Deaconess Road, West/RB 660, Boston, MA, USA.
Mario MoricDepartment of Anesthesiology, Rush University Medical Center, 1653 W. Congress Pkwy. Jelke 7 Chicago, IL, USA.
Xuanji WangDepartment of Surgery, Loyola University Medical Center, 2160 S. First Ave, Maywood, IL, USA.
Jessica KruseDepartment of Anesthesiology, Rush University Medical Center, 1653 W. Congress Pkwy. Jelke 7 Chicago, IL, USA.
Ariel MuellerDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, One Deaconess Road, West/RB 660, Boston, MA, USA.
Myles D BooneDepartment of Anesthesiology, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, New Hampshire, USA.
Cristina BarboiDepartment of Anesthesiology, Loyola University Medical Center, 2160 S. First Ave, Maywood, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsAlthough a risk-adjusted approach to preventing postoperative nausea and vomiting (PONV) is generally recommended, the successful implementation of such practice without mandated protocols remains elusive. To date, such a strategy has never been adapted to curb high baseline rates of prophylaxis. MATERIAL AND

methodsWe conducted an observational study on a cohort of patients undergoing elective surgery before and after the implementation of a quality improvement initiative including a risk-stratified approach to prevent PONV. The primary outcome was the number of prophylactic interventions administered. Secondary outcome included the repetition of ineffective medications and the need for rescue medication in the post-anesthesia care unit (PACU).

resultsA total of 636 patients were included; 325 patients during the control period and 311 after the intervention. The educational program failed to reduce the amount of prophylactic antiemetics administered (2.0 vs. 2.6,

conclusionImplementation of best practices to combat PONV remains elusive. Our results indicate that difficulties in changing provider behavior also apply to institutions with high prophylactic antiemetic administration rates.

Indexed as

Postoperative nausea and vomiting/diagnosispostoperative nausea and vomiting/prevention and controlpostoperative nausea and vomiting/therapyrisk factors

Identifiers

PMID34759561
PMCPMC8562445

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.