Evidence map›Paper›PMID 34759292›Full record

ArticleNature communications2021

A Fabry-Pérot cavity coupled surface plasmon photodiode for electrical biomolecular sensing.

Giles Allison, Amrita Kumar Sana, Yuta Ogawa, Hidemi Kato, Kosei Ueno, Hiroaki Misawa, Koki Hayashi, Hironori Suzuki

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giles AllisonIMRA Japan Co., Ltd., 2-36, Hachiken-cho, Kariya, Aichi, 448-8650, Japan. giles.allison@imra-japan.com.ORCID 0000-0002-4810-092X
Amrita Kumar SanaIMRA Japan Co., Ltd., 2-36, Hachiken-cho, Kariya, Aichi, 448-8650, Japan.ORCID 0000-0003-3505-1652
Yuta OgawaIMRA Japan Co., Ltd., 2-36, Hachiken-cho, Kariya, Aichi, 448-8650, Japan.
Hidemi KatoIMRA Japan Co., Ltd., 2-36, Hachiken-cho, Kariya, Aichi, 448-8650, Japan.
Kosei UenoDepartment of Chemistry, Faculty of Science, Hokkaido University, Kita-ku, Sapporo, 060-0810, Japan.ORCID 0000-0002-4882-7854
Hiroaki MisawaResearch Institute for Electronic Science, Hokkaido University, Kita-ku, Sapporo, 001-0021, Japan.ORCID 0000-0003-1070-387X
Koki HayashiIMRA Japan Co., Ltd., 2-36, Hachiken-cho, Kariya, Aichi, 448-8650, Japan.
Hironori SuzukiIMRA Japan Co., Ltd., 2-36, Hachiken-cho, Kariya, Aichi, 448-8650, Japan.ORCID 0000-0001-9754-4992

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surface plasmon resonance is a well-established technology for real-time highly sensitive label-free detection and measurement of binding kinetics between biological samples. A common drawback, however, of surface plasmon resonance detection is the necessity for far field angular resolved measurement of specular reflection, which increases the size as well as requiring precise calibration of the optical apparatus. Here we present an alternative optoelectronic approach in which the plasmonic sensor is integrated within a photovoltaic cell. Incident light generates an electronic signal that is sensitive to the refractive index of a solution via interaction with the plasmon. The photogenerated current is enhanced due to the coupling of the plasmon mode with Fabry-Pérot modes in the absorbing layer of the photovoltaic cell. The near field electrical detection of surface plasmon resonance we demonstrate will enable a next generation of cheap, compact and high throughput biosensors.

Indexed as

Biosensing TechniquesSurface Plasmon Resonance

Identifiers

PMID34759292
PMCPMC8580965

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.