Evidence map›Paper›PMID 34759276›Full record

ArticleScientific reports2021

Comparative analysis of default mode networks in major psychiatric disorders using resting-state EEG.

Kang-Min Choi, Jeong-Youn Kim, Yong-Wook Kim, Jung-Won Han, Chang-Hwan Im, Seung-Hwan Lee

Erratum issuedAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Kang-Min Choi *Clinical Emotion and Cognition Research Laboratory, Inje University, Goyang, Republic of Korea.
Jeong-Youn Kim *Center for Bionics, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
Yong-Wook KimClinical Emotion and Cognition Research Laboratory, Inje University, Goyang, Republic of Korea.
Jung-Won HanClinical Emotion and Cognition Research Laboratory, Inje University, Goyang, Republic of Korea.
Chang-Hwan ImSchool of Electronic Engineering, Hanyang University, Seoul, Republic of Korea. ich@hanyang.ac.kr.
Seung-Hwan LeeClinical Emotion and Cognition Research Laboratory, Inje University, Goyang, Republic of Korea. lshpss@paik.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Default mode network (DMN) is a set of functional brain structures coherently activated when individuals are in resting-state. In this study, we constructed multi-frequency band resting-state EEG-based DMN functional network models for major psychiatric disorders to easily compare their pathophysiological characteristics. Phase-locking values (PLVs) were evaluated to quantify functional connectivity; global and nodal clustering coefficients (CCs) were evaluated to quantify global and local connectivity patterns of DMN nodes, respectively. DMNs of patients with post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), panic disorder, major depressive disorder (MDD), bipolar disorder, schizophrenia (SZ), mild cognitive impairment (MCI), and Alzheimer's disease (AD) were constructed relative to their demographically-matched healthy control groups. Overall DMN patterns were then visualized and compared with each other. In global CCs, SZ and AD showed hyper-clustering in the theta band; OCD, MCI, and AD showed hypo-clustering in the low-alpha band; OCD and MDD showed hypo-clustering and hyper-clustering in low-beta, and high-beta bands, respectively. In local CCs, disease-specific patterns were observed. In the PLVs, lowered theta-band functional connectivity between the left lingual gyrus and the left hippocampus was frequently observed. Our comprehensive comparisons suggest EEG-based DMN as a useful vehicle for understanding altered brain networks of major psychiatric disorders.

Indexed as

Alzheimer DiseaseBipolar DisorderBrainBrain MappingCognitive DysfunctionElectroencephalographyHumansMajor Depressive DisorderNerve NetObsessive-Compulsive DisorderPanic DisorderSchizophreniaStress Disorders, Post-Traumatic

Identifiers

PMID34759276
PMCPMC8580995

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.