Evidence map›Paper›PMID 34758881›Full record

Trial reportAddiction science & clinical practice2021

Feasibility and acceptability of electronic administration of patient reported outcomes using mHealth platform in emergency department patients with non-medical opioid use.

Kathryn Hawk, Caitlin Malicki, Jeremiah Kinsman, Gail D'Onofrio, Andrew Taylor, Arjun Venkatesh

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Addiction science & clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03985163 (Capturing Opioid Use Disorder Electronically & Patient Reported Outcomes), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03985163 completednot on this map

Capturing Opioid Use Disorder Electronically & Patient Reported Outcomes

Typeobservational_patient_registrySponsorYale UniversityRan2019 to 2020Enrolled101ConditionsOpioid-use Disorder, Overdose of Opiate, Patient ParticipationArmsPatient Reported Outcomes Electronic Survey
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kathryn HawkDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA. kathryn.hawk@yale.edu.ORCID 0000-0001-7435-5945
Caitlin MalickiDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA.
Jeremiah KinsmanDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA.
Gail D'OnofrioDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA.
Andrew TaylorDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA.
Arjun VenkateshDepartment of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260, New Haven, CT, 06519, USA.

Funding

The National Drug Abuse Treatment Clinical Trials NetworkUG1DA015831 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Roger D. Weiss · 2015 to 2026
$110.8M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863NIDA NIH HHS UG1 DA015831NIDA NIH HHS UG1DA015831-18S2
6 · The paper itself

Abstract

backgroundThe emergency department (ED) offers an important opportunity to identify patients with opioid use disorder (OUD) and initiate treatment. However, post-ED follow-up is challenging, and novel approaches to enhance care transitions are urgently needed. Outcomes following ED visits have traditionally focused on overdose, treatment engagement, and mortality with an absence of patient reported outcomes (PROs), for example patient ability to schedule follow-up OUD treatment appointments or pick up a prescription medication, that may better inform evaluation of treatment pathways and near-term outcomes after acute events. In the context of increasing novel secure mobile health (mHealth) platforms, we explored the feasibility and acceptability of electronically collecting PROs from ED patients with non-medical opioid use to enhance care in the ED and transitions of care.

methodsED patients with non-medical opioid use or opioid overdose who endorsed willingness and ability to complete electronic surveys after discharge were enrolled from a tertiary, urban academic ED. Participants were enrolled in an mHealth platform, shared electronic health records with researchers, and completed electronic surveys of PROs at baseline, three- and thirty-days post discharge from the hospital, including questions about ability to schedule a follow-up appointment, pick up a prescription medication and overdose risk behaviors. Primary outcomes were measures of feasibility and acceptability of electronic PRO collection among ED patients with non-medical opioid use.

resultsAmong 1,808 patients assessed for eligibility between June-December 2019, 101 of 130 (78%) eligible adult patients consented to participate. Ninety-six (95%) of 101 patients completed registration in the mHealth platform, and 77/96 (80%) were successful in sharing their electronic health data. Completion rates for the baseline, three-day and thirty-day surveys were 97% (93/96), 49% (47/96) and 42% (40/96). Implementation challenges included short engagement window during ED visit, limited access to smartphones/computers, insufficient battery life of participant phone to access email and password, forgotten emails and passwords, multi-step verification processes for account set-up, and complaints about hospital care, most of which were effectively addressed by study personnel.

conclusionsED patients with OUD were willing to share electronic health information and PROs, although implementation challenges were common, and more than half of participants were lost-to-follow-up after hospital discharge at 30 days. Efforts to streamline communication and remove barriers to engagement are needed to improve the collection of PROs and pathways of care in ED patients with OUD. Clinical Trial Registration ClinicalTrials.gov (NCT03985163). Date of Registration: June 10, 2019, Retrospectively registered (First enrollment June 8, 2019). https://clinicaltrials.gov/ct2/show/record/NCT03985163.

Indexed as

Opioid-Related DisordersTelemedicineAdultAftercareAnalgesics, OpioidElectronicsEmergency Service, HospitalFeasibility StudiesHumansPatient DischargePatient Reported Outcome MeasuresAnalgesics, OpioidEmergency departmentmHealthMobile healthOpioid use disorderPatient reported outcome measures

Identifiers

PMID34758881
PMCPMC8579535

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.