Evidence map›Paper›PMID 34758818›Full record

ArticleRespiratory research2021

Comparison of airway pressures and expired gas washout for nasal high flow versus CPAP in child airway replicas.

Kelvin Duong, Michelle Noga, Joanna E MacLean, Warren H Finlay, Andrew R Martin

Open access · goldAbstract readComparative Study
In one paragraph

Article in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. An update on diagnosis and management of obstructive sleep apnoea in the first 2 years of life.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kelvin DuongDepartment of Mechanical Engineering, University of Alberta, Edmonton, Canada.
Michelle NogaDepartment of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada.
Joanna E MacLeanDepartment of Pediatrics and Women & Children's Health Research Institute, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada.
Warren H FinlayDepartment of Mechanical Engineering, University of Alberta, Edmonton, Canada.
Andrew R MartinDepartment of Mechanical Engineering, University of Alberta, Edmonton, Canada. andrew.martin@ualberta.ca.
University of Alberta · CAWomen and Children’s Health Research Institute · CA

Funding

Lung Association, Alberta and NWT RES0044295
6 · The paper itself

Abstract

backgroundFor children and adults, the standard treatment for obstructive sleep apnea is the delivery of continuous positive airway pressure (CPAP). Though effective, CPAP masks can be uncomfortable to patients, contributing to adherence concerns. Recently, nasal high flow (NHF) therapy has been investigated as an alternative, especially in CPAP-intolerant children. The present study aimed to compare and contrast the positive airway pressures and expired gas washout generated by NHF versus CPAP in child nasal airway replicas.

methodsNHF therapy was investigated at a flow rate of 20 L/min and compared to CPAP at 5 cmH

resultsNHF therapy generated an average positive end-expiratory pressure (PEEP) of 5.17 ± 2.09 cmH

conclusionIn child airway replicas, NHF at 20 L/min generated average PEEP similar to CPAP at 5 cm H

Indexed as

CannulaRespirationCarbon DioxideChildChild, PreschoolContinuous Positive Airway PressureFemaleHumansMaleSleep Apnea, ObstructiveTracheaCarbon DioxideAdherenceContinuous positive airway pressureEnd-tidal carbon dioxideNasal cannulaNasal high flowObstructive sleep apneaTracheal pressure

Identifiers

PMID34758818
PMCPMC8579677
OpenAlexW3213600031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.