Evidence map›Paper›PMID 34758686›Full record

ReviewExpert review of molecular diagnostics2021

Point-of-care COVID-19 testing in the emergency department: current status and future prospects.

Larissa May, Nam Tran, Nathan A Ledeboer

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of molecular diagnostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. 'CoviSwiftJournal of virological methods · 2023
    Article
  11. COVID-19 self-testing in Brazil and the imminent risk of underreporting cases.Revista da Sociedade Brasileira de Medicina Tropical · 2023
    Article
  12. Review
  13. False-positive XpertSaudi medical journal · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Larissa MayDavis Department of Emergency Medicine, University of California, Sacramento, CA, USA.
Nam TranDavis Department of Pathology and Laboratory Medicine, University of California, USA.
Nathan A LedeboerDepartment of Pathology and Laboratory Medicine, Medical College of Wisconsin, USA.
University of California, Davis · USMedical College of Wisconsin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis expert review outlines current and future point-of-care technologies for the diagnosis of the SARS-CoV-2 virus, which is responsible for causing coronavirus disease COVID-19 in the emergency department. COVID-19 first emerged in late 2019 and is responsible for a range of presentations from minor upper respiratory tract symptoms to severe pneumonia and multisystem organ failure. Among the technologies available include the gold standard of molecular point-of-care tests as well as antigen detection tests. AREAS COVERED: We discuss point-of-care molecular tests including multiplex, targeted, and single plex panels as well as various antigen testing methodologies in terms of availability and performance characteristics. In addition, we focus on current testing best practices and considerations for point-of-care testing in the emergency department based on a search of the literature available in PubMed to date and a review of FDA and CDC guidance. EXPERT OPINION: While there have been many advances in SARS-CoV-2 point-of-care testing, there remain challenges to implementation in the emergency department setting. A paradigm shift is needed to improve diagnosis and clinical outcomes.

Indexed as

COVID-19Point-of-Care TestingCOVID-19 TestingEmergency Service, HospitalHumansantigen testsCOVID-19molecularpoint-of-care diagnostics

Identifiers

PMID34758686
PMCPMC8631689
OpenAlexW3214517995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.