Coral Ecotoxicological Data Evaluation for the Environmental Safety Assessment of Ultraviolet Filters.

There is growing interest in the environmental safety of ultraviolet (UV) filters found in cosmetic and personal care products (CPCPs). The CPCP industry is assessing appropriate environmental risk assessment (ERA) methods to conduct robust environmental safety assessments for these ingredients. Relevant and reliable data are needed for ERA, particularly when the assessment is supporting regulatory decision-making. In the present study, we apply a data evaluation approach to incorporate nonstandard toxicity data into the ERA process through an expanded range of reliability scores over commonly used approaches (e.g., Klimisch scores). The method employs an upfront screening followed by a data quality assessment based largely on the Criteria for Reporting and Evaluating Ecotoxicity Data (CRED) approach. The method was applied in a coral case study in which UV filter toxicity data was evaluated to identify data points potentially suitable for higher tier and/or regulatory ERA. This is an optimal case study because there are no standard coral toxicity test methods, and UV filter bans are being enacted based on findings reported in the current peer-reviewed data set. Eight studies comprising nine assays were identified; four of the assays did not pass the initial screening assessment. None of the remaining five assays received a high enough reliability score (R