Evidence map›Paper›PMID 34758108›Full record

ArticleActa anaesthesiologica Scandinavica2022

Residual lung damage following ARDS in COVID-19 ICU survivors.

Nicola Compagnone, Diego Palumbo, George Cremona, Giordano Vitali, Rebecca De Lorenzo, Maria Rosa Calvi, Andrea Del Prete, Martina Baiardo Redaelli, Sabrina Calamarà, Alessandro Belletti and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Acta anaesthesiologica Scandinavica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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  14. COVID-19: Some unresolved issues.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
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  16. Residual lung damage following ARDS in COVID-19 ICU survivors.Acta anaesthesiologica Scandinavica · 2022
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Nicola CompagnoneVita-Salute San Raffaele University, Milan, Italy.
Diego PalumboVita-Salute San Raffaele University, Milan, Italy.
George CremonaUnit of Respiratory Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Giordano VitaliDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Hospital, Milan, Italy.
Rebecca De LorenzoVita-Salute San Raffaele University, Milan, Italy.
Maria Rosa CalviDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Andrea Del PreteClinical and Experimental Radiology Unit, Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Martina Baiardo RedaelliDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Sabrina CalamaràClinical and Experimental Radiology Unit, Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Alessandro BellettiDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0003-3131-0565
Stephanie SteidlerClinical and Experimental Radiology Unit, Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Caterina ConteDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Hospital, Milan, Italy.
Alberto ZangrilloVita-Salute San Raffaele University, Milan, Italy.
Francesco De CobelliVita-Salute San Raffaele University, Milan, Italy.
Patrizia Rovere-QueriniVita-Salute San Raffaele University, Milan, Italy.
COVID-BioB Study Group
Giacomo MontiDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-3885-9238
Vita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 acute respiratory distress syndrome (COVID-19 ARDS) is a disease that often requires invasive ventilation. Little is known about COVID-19 ARDS sequelae. We assessed the mid-term lung status of COVID-19 survivors and investigated factors associated with pulmonary sequelae.

methodsAll adult COVID-19 patients admitted to the intensive care unit from 25th February to 27th April 2020 were included. Lung function was evaluated through chest CT scan and pulmonary function tests (PFT). Logistic regression was used to identify predictors of persisting lung alterations.

resultsForty-nine patients (75%) completed lung assessment. Chest CT scan was performed after a median (interquartile range) time of 97 (89-105) days, whilst PFT after 142 (133-160) days. The median age was 58 (52-65) years and most patients were male (90%). The median duration of mechanical ventilation was 11 (6-16) days. Median tidal volume/ideal body weight (TV/IBW) was 6.8 (5.71-7.67) ml/Kg. 59% and 63% of patients showed radiological and functional lung sequelae, respectively. The diffusion capacity of carbon monoxide (DL

conclusionsBoth the extent of lung parenchymal involvement and mechanical ventilation protocols predict morphological and functional lung abnormalities months after COVID-19.

Indexed as

COVID-19Respiratory Distress SyndromeAdultHumansIntensive Care UnitsLungMaleMiddle AgedSARS-CoV-2Survivorsacute respiratory distress syndromechest CT scanCOVID-19critically ill patientsfollow-upintensive carepulmonary fibrosispulmonary function tests

Identifiers

PMID34758108
PMCPMC8652634
OpenAlexW3212793958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.